Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50362730'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50362730 (CHEMBL1939792) Show SMILES COc1cc(C)c2nc3[nH]nc(C)c3c(N3CCN([C@@H](C)C3)C(N)=O)c2c1 |r| Show InChI InChI=1S/C19H24N6O2/c1-10-7-13(27-4)8-14-16(10)21-18-15(12(3)22-23-18)17(14)24-5-6-25(19(20)26)11(2)9-24/h7-8,11H,5-6,9H2,1-4H3,(H2,20,26)(H,21,22,23)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE10A using [3H]cAMP as substrate by scintillation proximity assay				Bioorg Med Chem Lett 22: 1019-22 (2012) Article DOI: 10.1016/j.bmcl.2011.11.127 BindingDB Entry DOI: 10.7270/Q2BV7H3J
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