Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase type I-alpha regulatory subunit' and Ligand = 'BDBM50011236'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM50011236 (CHEMBL344314 | Isoquinoline-5-sulfonic acid (2-ami...) Show SMILES NCCNS(=O)(=O)c1cccc2cnccc12 Show InChI InChI=1S/C11H13N3O2S/c12-5-7-14-17(15,16)11-3-1-2-9-8-13-6-4-10(9)11/h1-4,6,8,14H,5,7,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	7.4	30
Nagoya University School of Medicine					Assay Description Casein kinase activities were determined under the conditions as described by Huang et al (1982).				J Biol Chem 264: 4924-7 (1989) BindingDB Entry DOI: 10.7270/Q2K072VK
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