Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM120862'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM120862 (US8716478, D248 | US9499570, D248) Show SMILES CC(=O)CCCOc1nc(Oc2cc3COB(O)c3c(F)c2)c(Cl)cc1C#N Show InChI InChI=1S/C18H15BClFN2O5/c1-10(24)3-2-4-26-17-11(8-22)6-14(20)18(23-17)28-13-5-12-9-27-19(25)16(12)15(21)7-13/h5-7,25H,2-4,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	37
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US8716478 (2014) BindingDB Entry DOI: 10.7270/Q2Z60MQ7
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