Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM14369'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM14369 (3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...) Show SMILES COc1ccc(Cn2cnc(N)c3nc(nc23)C(C)(C)OCc2ccc(C)cc2)cc1OC1CCCC1 Show InChI InChI=1S/C29H35N5O3/c1-19-9-11-20(12-10-19)17-36-29(2,3)28-32-25-26(30)31-18-34(27(25)33-28)16-21-13-14-23(35-4)24(15-21)37-22-7-5-6-8-22/h9-15,18,22H,5-8,16-17,30H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	206	-37.8	n/a	n/a	n/a	n/a	n/a	8.0	22
Purdue Pharma LP					Assay Description PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...				J Med Chem 48: 1237-43 (2005) Article DOI: 10.1021/jm030603w BindingDB Entry DOI: 10.7270/Q2GT5KF0
					More data for this Ligand-Target Pair