Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM30048'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM30048 (triazolothiadiazine, 42) Show SMILES COc1ccc(cc1O[C@@H]1CCOC1)C1=Nn2c(SC1)nnc2-c1ccccc1C(F)(F)F |r,t:16| Show InChI InChI=1S/C22H19F3N4O3S/c1-30-18-7-6-13(10-19(18)32-14-8-9-31-11-14)17-12-33-21-27-26-20(29(21)28-17)15-4-2-3-5-16(15)22(23,24)25/h2-7,10,14H,8-9,11-12H2,1H3/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	7.2	22
National Human Genome Research Institute					Assay Description Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...				Bioorg Med Chem Lett 19: 3686-92 (2009) Article DOI: 10.1016/j.bmcl.2009.01.057 BindingDB Entry DOI: 10.7270/Q2W37TNT
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