Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50074974'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50074974 (1-[2,5-Bis-(3,4-dimethoxy-phenyl)-furan-3-yl]-etha...) Show SMILES COc1ccc(cc1OC)-c1cc(C(C)=O)c(o1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C22H22O6/c1-13(23)16-12-19(14-6-8-17(24-2)20(10-14)26-4)28-22(16)15-7-9-18(25-3)21(11-15)27-5/h6-12H,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description PDE4A activity assessed using human recombinant purified GST-PDE4A248				Bioorg Med Chem Lett 9: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q27S7MXX
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