Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50125068'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50125068 (Benzyl-{5-[1-(3,4-bis-difluoromethoxy-phenyl)-2-(1...) Show SMILES CC(C)N(Cc1ccccc1)c1ccc(cn1)C(Cc1cc[n+]([O-])cc1)c1ccc(OC(F)F)c(OC(F)F)c1 Show InChI InChI=1S/C30H29F4N3O3/c1-20(2)37(19-22-6-4-3-5-7-22)28-11-9-24(18-35-28)25(16-21-12-14-36(38)15-13-21)23-8-10-26(39-29(31)32)27(17-23)40-30(33)34/h3-15,17-18,20,25,29-30H,16,19H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against human PDE4A expressed isoform using construct representing the common region of spliced variants as GST-fusion protein in...				Bioorg Med Chem Lett 13: 741-4 (2003) BindingDB Entry DOI: 10.7270/Q2PG1R3G
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