Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50150129'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50150129 (CHEMBL3771255) Show SMILES CC(C)[C@@H]1CN2C(=N1)N(C)C(=O)c1c2nn(Cc2ccc(cc2)-c2ccccc2)c1Nc1ccccc1 |r,c:6| Show InChI InChI=1S/C30H30N6O/c1-20(2)25-19-35-28-26(29(37)34(3)30(35)32-25)27(31-24-12-8-5-9-13-24)36(33-28)18-21-14-16-23(17-15-21)22-10-6-4-7-11-22/h4-17,20,25,31H,18-19H2,1-3H3/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Intra-Cellular Therapies, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant full lenght human PDE4A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assay				J Med Chem 59: 1149-64 (2016) Article DOI: 10.1021/acs.jmedchem.5b01751 BindingDB Entry DOI: 10.7270/Q2X068W7
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