Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50150132'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50150132 (CHEMBL3770009) Show SMILES CN1C2=N[C@H](Cc3ccccc3)CN2c2nn(Cc3ccc(cc3)-c3ccccc3)c(Nc3ccccc3)c2C1=O |r,t:2| Show InChI InChI=1S/C34H30N6O/c1-38-33(41)30-31(35-28-15-9-4-10-16-28)40(22-25-17-19-27(20-18-25)26-13-7-3-8-14-26)37-32(30)39-23-29(36-34(38)39)21-24-11-5-2-6-12-24/h2-20,29,35H,21-23H2,1H3/t29-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Intra-Cellular Therapies, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant full lenght human PDE4A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assay				J Med Chem 59: 1149-64 (2016) Article DOI: 10.1021/acs.jmedchem.5b01751 BindingDB Entry DOI: 10.7270/Q2X068W7
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