Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50150261'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50150261 (CHEMBL3771172) Show SMILES [H][C@@]12CCC[C@]1([H])N1C3N(Cc4ccc(cc4)-c4ccc(F)cc4)NC(Nc4ccccc4)=C3C(=O)N(C)C1=N2 |r,c:36,44| Show InChI InChI=1S/C30H29FN6O/c1-35-29(38)26-27(32-23-6-3-2-4-7-23)34-36(28(26)37-25-9-5-8-24(25)33-30(35)37)18-19-10-12-20(13-11-19)21-14-16-22(31)17-15-21/h2-4,6-7,10-17,24-25,28,32,34H,5,8-9,18H2,1H3/t24-,25+,28?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Intra-Cellular Therapies, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant full lenght human PDE4A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assay				J Med Chem 59: 1149-64 (2016) Article DOI: 10.1021/acs.jmedchem.5b01751 BindingDB Entry DOI: 10.7270/Q2X068W7
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