Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM120856'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM120856 (US8716478, D242 | US9499570, D242) Show SMILES CC(=O)CCCOc1nc(Oc2ccc3B(O)OCc3c2)cc(c1C#N)C(F)(F)F Show InChI InChI=1S/C19H16BF3N2O5/c1-11(26)3-2-6-28-18-14(9-24)15(19(21,22)23)8-17(25-18)30-13-4-5-16-12(7-13)10-29-20(16)27/h4-5,7-8,27H,2-3,6,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.5	n/a
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US9499570 (2016) BindingDB Entry DOI: 10.7270/Q2CZ363N
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