Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM120860'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM120860 (US8716478, D246 | US9499570, D246) Show SMILES CC(=O)CCCOc1nc(Oc2cc3COB(O)c3c(C)c2)c(Cl)cc1C#N Show InChI InChI=1S/C19H18BClN2O5/c1-11-6-15(7-14-10-27-20(25)17(11)14)28-19-16(21)8-13(9-22)18(23-19)26-5-3-4-12(2)24/h6-8,25H,3-5,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	n/a
Anacor Pharmaceuticals, Inc. US Patent					Assay Description Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...				US Patent US9499570 (2016) BindingDB Entry DOI: 10.7270/Q2CZ363N
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