Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM285597'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM285597 (3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...) Show SMILES Cc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)N[C@@H]1C[C@@H]1F |r,wU:20.22,22.26,(-3.54,.88,;-2.05,1.28,;-1.66,2.76,;-.17,3.16,;.23,4.65,;.92,2.07,;.52,.59,;-.96,.19,;-1.36,-1.3,;-.46,-2.55,;-1.36,-3.79,;-2.83,-3.32,;-4.16,-4.09,;-5.5,-3.32,;-5.5,-1.78,;-4.16,-1.01,;-2.83,-1.78,;1.08,-2.55,;1.85,-1.21,;1.85,-3.88,;3.39,-3.88,;4.73,-4.65,;4.73,-3.11,;5.5,-1.78,)| Show InChI InChI=1S/C17H14ClFN4O/c1-9-7-10(18)4-5-11(9)16-15(17(24)21-13-8-12(13)19)22-14-3-2-6-20-23(14)16/h2-7,12-13H,8H2,1H3,(H,21,24)/t12-,13+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...				US Patent US10669279 (2020) BindingDB Entry DOI: 10.7270/Q2765JC9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM285597 (3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...) Show SMILES Cc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)N[C@@H]1C[C@@H]1F |r,wU:20.22,22.26,(-3.54,.88,;-2.05,1.28,;-1.66,2.76,;-.17,3.16,;.23,4.65,;.92,2.07,;.52,.59,;-.96,.19,;-1.36,-1.3,;-.46,-2.55,;-1.36,-3.79,;-2.83,-3.32,;-4.16,-4.09,;-5.5,-3.32,;-5.5,-1.78,;-4.16,-1.01,;-2.83,-1.78,;1.08,-2.55,;1.85,-1.21,;1.85,-3.88,;3.39,-3.88,;4.73,-4.65,;4.73,-3.11,;5.5,-1.78,)| Show InChI InChI=1S/C17H14ClFN4O/c1-9-7-10(18)4-5-11(9)16-15(17(24)21-13-8-12(13)19)22-14-3-2-6-20-23(14)16/h2-7,12-13H,8H2,1H3,(H,21,24)/t12-,13+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent									US Patent US9598421 (2017) BindingDB Entry DOI: 10.7270/Q2K939KG
					More data for this Ligand-Target Pair