Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50023412'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50023412 (CHEMBL3327321) Show SMILES FC(F)Oc1ccc(cc1OCCCSC1CCOC1=O)C(=O)Nc1c(Cl)cncc1Cl Show InChI InChI=1S/C20H18Cl2F2N2O5S/c21-12-9-25-10-13(22)17(12)26-18(27)11-2-3-14(31-20(23)24)15(8-11)29-5-1-7-32-16-4-6-30-19(16)28/h2-3,8-10,16,20H,1,4-7H2,(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Amakem N.V. Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assay				Bioorg Med Chem Lett 24: 4594-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.016 BindingDB Entry DOI: 10.7270/Q21C1ZFH
					More data for this Ligand-Target Pair