Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50205610'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50205610 (CHEMBL3926566) Show SMILES COc1ccc(cc1OC)C1=NN(CCCO)C(=O)CCC1 |t:11| Show InChI InChI=1S/C16H22N2O4/c1-21-14-8-7-12(11-15(14)22-2)13-5-3-6-16(20)18(17-13)9-4-10-19/h7-8,11,19H,3-6,9-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assay				Bioorg Med Chem Lett 27: 24-29 (2017) Article DOI: 10.1016/j.bmcl.2016.11.040 BindingDB Entry DOI: 10.7270/Q21N8333
					More data for this Ligand-Target Pair