Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50208314 (CHEMBL3884788) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 166 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Medical University Curated by ChEMBL | Assay Description Inhibition of full length human PDE4B1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assay | Eur J Med Chem 124: 372-379 (2016) Article DOI: 10.1016/j.ejmech.2016.08.052 BindingDB Entry DOI: 10.7270/Q29P33N6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50208314 (CHEMBL3884788) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Medical University Curated by ChEMBL | Assay Description Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr b... | Eur J Med Chem 168: 221-231 (2019) Article DOI: 10.1016/j.ejmech.2019.02.026 BindingDB Entry DOI: 10.7270/Q28W3HQT | |||||||||||
More data for this Ligand-Target Pair |