Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50219269'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50219269 ((5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)q...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CC1)C(=O)c1nc(oc1CN)-c1ccc(OC)c2nc(ccc12)C(F)(F)F Show InChI InChI=1S/C26H26F3N7O5/c1-38-16-6-4-15(14-5-7-18(26(27,28)29)31-21(14)16)23-34-22(17(13-30)41-23)24(37)35-8-10-36(11-9-35)25-32-19(39-2)12-20(33-25)40-3/h4-7,12H,8-11,13,30H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 17: 5150-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.092 BindingDB Entry DOI: 10.7270/Q2862G4H
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