Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50219274'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50219274 (8-[5-aminomethyl-2-(8-methoxy-2-trifluoromethyl-qu...) Show SMILES COc1ccc(-c2nc(C(=O)N3CCC4(CC3)N(CNC4=O)c3ccccc3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C29H27F3N6O4/c1-41-20-9-7-19(18-8-10-22(29(30,31)32)35-23(18)20)25-36-24(21(15-33)42-25)26(39)37-13-11-28(12-14-37)27(40)34-16-38(28)17-5-3-2-4-6-17/h2-10H,11-16,33H2,1H3,(H,34,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 17: 5150-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.092 BindingDB Entry DOI: 10.7270/Q2862G4H
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