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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50314567'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50314567
PNG
(CHEMBL1090031 | cyclopentyl(4-(3-(4-(3-fluoropheny...)
Show SMILES Fc1cccc(c1)-c1nnc(NCCCN2CCN(CC2)C(=O)C2CCCC2)c2cc3ccccn3c12
Show InChI InChI=1S/C29H33FN6O/c30-23-10-5-9-22(19-23)26-27-25(20-24-11-3-4-14-36(24)27)28(33-32-26)31-12-6-13-34-15-17-35(18-16-34)29(37)21-7-1-2-8-21/h3-5,9-11,14,19-21H,1-2,6-8,12-13,15-18H2,(H,31,33)
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.40E+4n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation counting


Bioorg Med Chem Lett 20: 2163-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.044
BindingDB Entry DOI: 10.7270/Q2NK3F54
More data for this
Ligand-Target Pair