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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50314571'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50314571
PNG
((4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizi...)
Show SMILES Fc1cccc(c1)-c1nnc(NCCCN2CCN(CC2)C(=O)c2ccccn2)c2cc3ccccn3c12
Show InChI InChI=1S/C29H28FN7O/c30-22-8-5-7-21(19-22)26-27-24(20-23-9-2-4-14-37(23)27)28(34-33-26)32-12-6-13-35-15-17-36(18-16-35)29(38)25-10-1-3-11-31-25/h1-5,7-11,14,19-20H,6,12-13,15-18H2,(H,32,34)
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Similars
Article
PubMed
 241n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation counting

Bioorg Med Chem Lett 20: 2163-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.044
BindingDB Entry DOI: 10.7270/Q2NK3F54
More data for this
Ligand-Target Pair