Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50353707'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50353707 (CHEMBL1830791) Show SMILES CC1(C)CCc2c(Nc3c(Cl)cncc3Cl)nc3oc4c(NCc5cccnc5)ncnc4c3c2C1 Show InChI InChI=1S/C26H23Cl2N7O/c1-26(2)6-5-15-16(8-26)19-21-22(24(33-13-32-21)31-10-14-4-3-7-29-9-14)36-25(19)35-23(15)34-20-17(27)11-30-12-18(20)28/h3-4,7,9,11-13H,5-6,8,10H2,1-2H3,(H,30,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assay				Eur J Med Chem 46: 4946-56 (2011) Article DOI: 10.1016/j.ejmech.2011.07.054 BindingDB Entry DOI: 10.7270/Q2VM4CPM
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