Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50363912'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50363912 (CHEMBL1946936) Show SMILES COc1ccc(C2=NNC(=O)CC2C)c2[nH]c(nc12)C(F)(F)F |t:6| Show InChI InChI=1S/C14H13F3N4O2/c1-6-5-9(22)20-21-10(6)7-3-4-8(23-2)12-11(7)18-13(19-12)14(15,16)17/h3-4,6H,5H2,1-2H3,(H,18,19)(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDE4B catalytic domain				Bioorg Med Chem 20: 1644-58 (2012) Article DOI: 10.1016/j.bmc.2012.01.033 BindingDB Entry DOI: 10.7270/Q2DB829P
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