Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50365056'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50365056 (CHEMBL1951065) Show SMILES COc1ccc(cc1OC)C1=NN(CCNCC(O)c2ccc(O)c(NC=O)c2)C(=O)C2CCCCC12 |t:11| Show InChI InChI=1S/C27H34N4O6/c1-36-24-10-8-18(14-25(24)37-2)26-19-5-3-4-6-20(19)27(35)31(30-26)12-11-28-15-23(34)17-7-9-22(33)21(13-17)29-16-32/h7-10,13-14,16,19-20,23,28,33-34H,3-6,11-12,15H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assay				Bioorg Med Chem Lett 22: 1523-6 (2012) Article DOI: 10.1016/j.bmcl.2012.01.013 BindingDB Entry DOI: 10.7270/Q2794548
					More data for this Ligand-Target Pair