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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50365060'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50365060
PNG
(CHEMBL1951069)
Show SMILES COc1ccc(cc1OC)C1=NN(CCCCCNCC(O)c2ccc(O)c(NC=O)c2)C(=O)C2CCCCC12 |t:11|
Show InChI InChI=1S/C30H40N4O6/c1-39-27-13-11-21(17-28(27)40-2)29-22-8-4-5-9-23(22)30(38)34(33-29)15-7-3-6-14-31-18-26(37)20-10-12-25(36)24(16-20)32-19-35/h10-13,16-17,19,22-23,26,31,36-37H,3-9,14-15,18H2,1-2H3,(H,32,35)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 257n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assay


Bioorg Med Chem Lett 22: 1523-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.013
BindingDB Entry DOI: 10.7270/Q2794548
More data for this
Ligand-Target Pair