Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50366135'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50366135 (CHEMBL1957302) Show SMILES COc1ccc2c(c[nH]c2c1)-c1nc2ccccc2cc1C#N Show InChI InChI=1S/C19H13N3O/c1-23-14-6-7-15-16(11-21-18(15)9-14)19-13(10-20)8-12-4-2-3-5-17(12)22-19/h2-9,11,21H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	890	n/a	n/a	n/a	n/a
University of Hyderabad Campus Curated by ChEMBL					Assay Description Inhibition of PDE4B expressed in HEK293 cells assessed as fold reduction in forskolin-stimulated cAMP production pretreated for 30 mins measured 4 hr...				Bioorg Med Chem 20: 2199-207 (2012) Article DOI: 10.1016/j.bmc.2012.02.027 BindingDB Entry DOI: 10.7270/Q28S4QDM
					More data for this Ligand-Target Pair