Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM285546'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM285546 (3-(4-cyano-5-fluoro-2-methylphenyl)-N-cyclo-propyl...) Show SMILES Cc1cc(C#N)c(F)cc1-c1c(nc2cccnn12)C(=O)NC1CC1 |(2.81,-8.2,;4.3,-7.8,;4.7,-6.31,;6.18,-5.91,;6.58,-4.42,;6.9,-2.92,;7.27,-7,;8.76,-6.6,;6.88,-8.49,;5.39,-8.89,;4.99,-10.37,;5.89,-11.62,;4.99,-12.87,;3.52,-12.39,;2.19,-13.16,;.86,-12.39,;.86,-10.85,;2.19,-10.08,;3.52,-10.85,;7.43,-11.62,;8.2,-10.29,;8.2,-12.95,;9.74,-12.95,;11.08,-13.72,;11.08,-12.18,)| Show InChI InChI=1S/C18H14FN5O/c1-10-7-11(9-20)14(19)8-13(10)17-16(18(25)22-12-4-5-12)23-15-3-2-6-21-24(15)17/h2-3,6-8,12H,4-5H2,1H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	645	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...				US Patent US10669279 (2020) BindingDB Entry DOI: 10.7270/Q2765JC9
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM285546 (3-(4-cyano-5-fluoro-2-methylphenyl)-N-cyclo-propyl...) Show SMILES Cc1cc(C#N)c(F)cc1-c1c(nc2cccnn12)C(=O)NC1CC1 |(2.81,-8.2,;4.3,-7.8,;4.7,-6.31,;6.18,-5.91,;6.58,-4.42,;6.9,-2.92,;7.27,-7,;8.76,-6.6,;6.88,-8.49,;5.39,-8.89,;4.99,-10.37,;5.89,-11.62,;4.99,-12.87,;3.52,-12.39,;2.19,-13.16,;.86,-12.39,;.86,-10.85,;2.19,-10.08,;3.52,-10.85,;7.43,-11.62,;8.2,-10.29,;8.2,-12.95,;9.74,-12.95,;11.08,-13.72,;11.08,-12.18,)| Show InChI InChI=1S/C18H14FN5O/c1-10-7-11(9-20)14(19)8-13(10)17-16(18(25)22-12-4-5-12)23-15-3-2-6-21-24(15)17/h2-3,6-8,12H,4-5H2,1H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	645	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent									US Patent US9598421 (2017) BindingDB Entry DOI: 10.7270/Q2K939KG
					More data for this Ligand-Target Pair