Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50097487 (CHEMBL3585874) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of PDE4D (unknown origin) | Citation and Details Article DOI: 10.1021/acs.jmedchem.9b02170 BindingDB Entry DOI: 10.7270/Q2W95DVV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50097487 (CHEMBL3585874) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Genoa Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate by fluorescence polarization assay | Bioorg Med Chem 23: 3426-35 (2015) Article DOI: 10.1016/j.bmc.2015.04.027 BindingDB Entry DOI: 10.7270/Q2NC62ZZ | |||||||||||
More data for this Ligand-Target Pair |