Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against PDE2 by scintillation proximity assay | Bioorg Med Chem Lett 16: 307-10 (2005) Article DOI: 10.1016/j.bmcl.2005.10.005 BindingDB Entry DOI: 10.7270/Q2XD118H | |||||||||||
More data for this Ligand-Target Pair |