Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent protein kinase' and Ligand = 'BDBM50265397'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265397 (4-[7-(1-Dimethylaminoethyl)-2-(4-fluorophenyl)imid...) Show SMILES CC(N(C)C)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C21H21FN6/c1-13(27(2)3)15-9-11-28-18(12-15)26-19(14-4-6-16(22)7-5-14)20(28)17-8-10-24-21(23)25-17/h4-13H,1-3H3,(H2,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0670	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265397 (4-[7-(1-Dimethylaminoethyl)-2-(4-fluorophenyl)imid...) Show SMILES CC(N(C)C)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C21H21FN6/c1-13(27(2)3)15-9-11-28-18(12-15)26-19(14-4-6-16(22)7-5-14)20(28)17-8-10-24-21(23)25-17/h4-13H,1-3H3,(H2,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0670	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265397 (4-[7-(1-Dimethylaminoethyl)-2-(4-fluorophenyl)imid...) Show SMILES CC(N(C)C)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C21H21FN6/c1-13(27(2)3)15-9-11-28-18(12-15)26-19(14-4-6-16(22)7-5-14)20(28)17-8-10-24-21(23)25-17/h4-13H,1-3H3,(H2,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair