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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM131009'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM131009
PNG
(US8829000, 82)
Show SMILES CCOc1cc2c(cc1C(=O)N(C)C)[nH]c(=O)c1cnc(C3CCCCC3)n21
Show InChI InChI=1S/C21H26N4O3/c1-4-28-18-11-16-15(10-14(18)21(27)24(2)3)23-20(26)17-12-22-19(25(16)17)13-8-6-5-7-9-13/h10-13H,4-9H2,1-3H3,(H,23,26)
PDB
MMDB

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PC sid
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US Patent
n/an/a>1.00E+4n/an/an/an/an/a30



ASKA Pharmaceutical Co., Ltd.

US Patent


Assay Description
By a method similar to the measurement of PDE9-inhibiting activity, PDE5-inhibiting activity of each of the test compounds was measured, percent inhi...


US Patent US8829000 (2014)


BindingDB Entry DOI: 10.7270/Q2K072ZX
More data for this
Ligand-Target Pair