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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM131011'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM131011
PNG
(US8829000, 86)
Show SMILES OCCN1CCN(CC1)C(=O)c1cc2[nH]c(=O)c3cnc(C4CCCCC4)n3c2cc1Cl
Show InChI InChI=1S/C23H28ClN5O3/c24-17-13-19-18(12-16(17)23(32)28-8-6-27(7-9-28)10-11-30)26-22(31)20-14-25-21(29(19)20)15-4-2-1-3-5-15/h12-15,30H,1-11H2,(H,26,31)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 7.54E+3n/an/an/an/an/a30



ASKA Pharmaceutical Co., Ltd.

US Patent


Assay Description
By a method similar to the measurement of PDE9-inhibiting activity, PDE5-inhibiting activity of each of the test compounds was measured, percent inhi...


US Patent US8829000 (2014)


BindingDB Entry DOI: 10.7270/Q2K072ZX
More data for this
Ligand-Target Pair