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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM131014'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM131014
PNG
(US8829000, 187)
Show SMILES OC(=O)CCc1ncc2n1c1ccc(cc1[nH]c2=O)C(F)(F)F
Show InChI InChI=1S/C14H10F3N3O3/c15-14(16,17)7-1-2-9-8(5-7)19-13(23)10-6-18-11(20(9)10)3-4-12(21)22/h1-2,5-6H,3-4H2,(H,19,23)(H,21,22)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 6.37E+3n/an/an/an/an/a30



ASKA Pharmaceutical Co., Ltd.

US Patent


Assay Description
By a method similar to the measurement of PDE9-inhibiting activity, PDE5-inhibiting activity of each of the test compounds was measured, percent inhi...


US Patent US8829000 (2014)


BindingDB Entry DOI: 10.7270/Q2K072ZX
More data for this
Ligand-Target Pair