Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50050588'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050588 (1-tert-Butyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dih...) Show SMILES CCCOc1ccccc1-c1nc2n(nc(C)c2c(=O)[nH]1)C(C)(C)C Show InChI InChI=1S/C19H24N4O2/c1-6-11-25-14-10-8-7-9-13(14)16-20-17-15(18(24)21-16)12(2)22-23(17)19(3,4)5/h7-10H,6,11H2,1-5H3,(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Rattus norvegicus)	BDBM50050588 (1-tert-Butyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dih...) Show SMILES CCCOc1ccccc1-c1nc2n(nc(C)c2c(=O)[nH]1)C(C)(C)C Show InChI InChI=1S/C19H24N4O2/c1-6-11-25-14-10-8-7-9-13(14)16-20-17-15(18(24)21-16)12(2)22-23(17)19(3,4)5/h7-10H,6,11H2,1-5H3,(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair