BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50050593'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050593 (1,3-Dimethyl-6-[5-(2-phenyl-thiazol-4-yl)-2-propox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Rattus norvegicus)	BDBM50050593 (1,3-Dimethyl-6-[5-(2-phenyl-thiazol-4-yl)-2-propox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair