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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50297818'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50297818
PNG
(6-(3,5-dimethylisoxazol-4-yl)-2-(2-morpholinoethyl...)
Show SMILES CCCOCCn1c2nc(ccc2nc(NCCN2CCOCC2)c1=O)-c1c(C)noc1C
Show InChI InChI=1S/C23H32N6O4/c1-4-12-31-15-11-29-22-19(6-5-18(26-22)20-16(2)27-33-17(20)3)25-21(23(29)30)24-7-8-28-9-13-32-14-10-28/h5-6H,4,7-15H2,1-3H3,(H,24,25)
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of PDE5

Bioorg Med Chem Lett 19: 4088-91 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.012
BindingDB Entry DOI: 10.7270/Q23R0SXR
More data for this
Ligand-Target Pair