Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50316641'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50316641 (1-(2-ethoxyethyl)-3-methyl-N7-(4-methylpyridin-2-y...) Show SMILES CCOCCn1nc(C)c2nc(NC3CCOCC3)nc(Nc3cc(C)ccn3)c12 Show InChI InChI=1S/C21H29N7O2/c1-4-29-12-9-28-19-18(15(3)27-28)25-21(23-16-6-10-30-11-7-16)26-20(19)24-17-13-14(2)5-8-22-17/h5,8,13,16H,4,6-7,9-12H2,1-3H3,(H2,22,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assay				Bioorg Med Chem Lett 20: 3120-4 (2010) BindingDB Entry DOI: 10.7270/Q2K64K0H
					More data for this Ligand-Target Pair