Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50316649'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50316649 (1-(2-ethoxyethyl)-3-methyl-5-(piperazin-1-yl)-N-(p...) Show SMILES CCOCCn1nc(C)c2nc(nc(Nc3ccccn3)c12)N1CCNCC1 Show InChI InChI=1S/C19H26N8O/c1-3-28-13-12-27-17-16(14(2)25-27)23-19(26-10-8-20-9-11-26)24-18(17)22-15-6-4-5-7-21-15/h4-7,20H,3,8-13H2,1-2H3,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assay				Bioorg Med Chem Lett 20: 3120-4 (2010) BindingDB Entry DOI: 10.7270/Q2K64K0H
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