Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50316650'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50316650 (1-(2-ethoxyethyl)-3-ethyl-5-(piperazin-1-yl)-N-(py...) Show SMILES CCOCCn1nc(CC)c2nc(nc(Nc3ccccn3)c12)N1CCNCC1 Show InChI InChI=1S/C20H28N8O/c1-3-15-17-18(28(26-15)13-14-29-4-2)19(23-16-7-5-6-8-22-16)25-20(24-17)27-11-9-21-10-12-27/h5-8,21H,3-4,9-14H2,1-2H3,(H,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 20: 3125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.03.106 BindingDB Entry DOI: 10.7270/Q2WH2QXD
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50316650 (1-(2-ethoxyethyl)-3-ethyl-5-(piperazin-1-yl)-N-(py...) Show SMILES CCOCCn1nc(CC)c2nc(nc(Nc3ccccn3)c12)N1CCNCC1 Show InChI InChI=1S/C20H28N8O/c1-3-15-17-18(28(26-15)13-14-29-4-2)19(23-16-7-5-6-8-22-16)25-20(24-17)27-11-9-21-10-12-27/h5-8,21H,3-4,9-14H2,1-2H3,(H,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assay				Bioorg Med Chem Lett 20: 3120-4 (2010) BindingDB Entry DOI: 10.7270/Q2K64K0H
					More data for this Ligand-Target Pair