Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50318145'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50318145 (5-(1,4-diazepan-1-yl)-3-methyl-N-(pyrimidin-4-yl)-...) Show SMILES Cc1nn(CCOCC(F)(F)F)c2c(Nc3ccncn3)nc(nc12)N1CCCNCC1 Show InChI InChI=1S/C19H24F3N9O/c1-13-15-16(31(29-13)9-10-32-11-19(20,21)22)17(26-14-3-5-24-12-25-14)28-18(27-15)30-7-2-4-23-6-8-30/h3,5,12,23H,2,4,6-11H2,1H3,(H,24,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 20: 3125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.03.106 BindingDB Entry DOI: 10.7270/Q2WH2QXD
					More data for this Ligand-Target Pair