Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50318149'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50318149 ((S)-3-methyl-5-(3-methylpiperazin-1-yl)-N-(pyrimid...) Show SMILES C[C@H]1CN(CCN1)c1nc(Nc2ccncn2)c2n(CCOCC(F)(F)F)nc(C)c2n1 |r| Show InChI InChI=1S/C19H24F3N9O/c1-12-9-30(6-5-24-12)18-27-15-13(2)29-31(7-8-32-10-19(20,21)22)16(15)17(28-18)26-14-3-4-23-11-25-14/h3-4,11-12,24H,5-10H2,1-2H3,(H,23,25,26,27,28)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 20: 3125-8 (2010) Article DOI: 10.1016/j.bmcl.2010.03.106 BindingDB Entry DOI: 10.7270/Q2WH2QXD
					More data for this Ligand-Target Pair