Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50359790'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359790 (CHEMBL1928253) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c(CC)n(CC3CC3)nc2c(=O)[nH]1 Show InChI InChI=1S/C25H35N7O5S/c1-4-20-21-22(29-32(20)16-17-6-7-17)24(33)28-23(27-21)19-14-18(15-26-25(19)37-13-12-36-3)38(34,35)31-10-8-30(5-2)9-11-31/h14-15,17H,4-13,16H2,1-3H3,(H,27,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
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