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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'p53-binding protein Mdm2' and Ligand = 'BDBM224650'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
p53-binding protein Mdm2


(Homo sapiens (Human))
BDBM224650
PNG
(3-[6-{[(1r)-1- cyclobutylethyl]amino}-7- [(trans-4...)
Show SMILES C[C@@H](Nc1nc(nc2nc(Sc3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)-c1noc(=O)[nH]1)C1CCC1 |r,wU:1.0,19.19,wD:22.23,(-4.31,-1.82,;-2.98,-2.59,;-1.64,-1.82,;-1.64,-.28,;-2.98,.49,;-2.98,2.03,;-1.64,2.8,;-.31,2.03,;1.16,2.51,;2.06,1.26,;3.6,1.26,;4.37,2.6,;5.91,2.6,;6.68,3.93,;5.91,5.26,;4.37,5.26,;3.6,3.93,;1.16,.02,;1.16,-1.52,;2.49,-2.29,;3.82,-1.52,;5.16,-2.29,;5.16,-3.83,;6.49,-4.6,;3.82,-4.6,;2.49,-3.83,;-.31,.49,;-4.31,2.8,;-5.78,2.33,;-6.68,3.57,;-5.78,4.82,;-6.17,6.31,;-4.31,4.34,;-2.98,-4.13,;-4.07,-5.22,;-2.98,-6.31,;-1.89,-5.22,)|
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.763n/an/an/an/an/a25



Merck Sharp & Dohme Corp.

US Patent




US Patent US9540377 (2017)


BindingDB Entry DOI: 10.7270/Q2RF5X1F
More data for this
Ligand-Target Pair