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Compile Data Set for Download or QSAR

Found 43 hits of Enz. Inhib. data with enzyme = 'Interleukin-8' and Substrate = 'to-be-curated'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-8


(Homo sapiens (Human))		BDBM277687
PNG
(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-me...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCC2CC(CO2)C(O)=O)c1
Show InChI InChI=1S/C43H49N5O11S/c1-43(2,3)27-18-36(40(55-5)37(19-27)48-60(6,52)53)47-42(51)46-35-11-12-38(34-10-8-7-9-33(34)35)59-29-13-14-44-39(23-29)45-28-20-30(54-4)22-31(21-28)57-16-15-56-25-32-17-26(24-58-32)41(49)50/h7-14,18-23,26,32,48H,15-17,24-25H2,1-6H3,(H,44,45)(H,49,50)(H2,46,47,51)
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n/an/a 2.80n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277693
PNG
(2-((2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCSCC(O)=O)c1
Show InChI InChI=1S/C41H47N5O10S2/c1-41(2,3)26-19-34(39(53-5)35(20-26)46-58(6,50)51)45-40(49)44-33-11-12-36(32-10-8-7-9-31(32)33)56-28-13-14-42-37(24-28)43-27-21-29(52-4)23-30(22-27)55-16-15-54-17-18-57-25-38(47)48/h7-14,19-24,46H,15-18,25H2,1-6H3,(H,42,43)(H,47,48)(H2,44,45,49)
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n/an/a 2.90n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277686
PNG
(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCc2cc(co2)C(O)=O)c1
Show InChI InChI=1S/C43H45N5O11S/c1-43(2,3)27-18-36(40(55-5)37(19-27)48-60(6,52)53)47-42(51)46-35-11-12-38(34-10-8-7-9-33(34)35)59-29-13-14-44-39(23-29)45-28-20-30(54-4)22-31(21-28)57-16-15-56-25-32-17-26(24-58-32)41(49)50/h7-14,17-24,48H,15-16,25H2,1-6H3,(H,44,45)(H,49,50)(H2,46,47,51)
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n/an/a 5.60n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277702
PNG
(5-((2-(3-((4-((4-(3-(5-tert-Butyl)-2-methoxy-3-(me...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCc2cc(cs2)C(O)=O)c1
Show InChI InChI=1S/C43H45N5O10S2/c1-43(2,3)27-18-36(40(55-5)37(19-27)48-60(6,52)53)47-42(51)46-35-11-12-38(34-10-8-7-9-33(34)35)58-29-13-14-44-39(23-29)45-28-20-30(54-4)22-31(21-28)57-16-15-56-24-32-17-26(25-59-32)41(49)50/h7-14,17-23,25,48H,15-16,24H2,1-6H3,(H,44,45)(H,49,50)(H2,46,47,51)
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Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277688
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOC(C)C(O)=O)c1
Show InChI InChI=1S/C42H49N5O11S/c1-26(40(48)49)56-18-16-55-17-19-57-31-23-28(22-30(24-31)53-5)44-38-25-29(14-15-43-38)58-37-13-12-34(32-10-8-9-11-33(32)37)45-41(50)46-35-20-27(42(2,3)4)21-36(39(35)54-6)47-59(7,51)52/h8-15,20-26,47H,16-19H2,1-7H3,(H,43,44)(H,48,49)(H2,45,46,50)
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Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277682
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(c4OC)S(C)=O)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(O)=O)c1
Show InChI InChI=1S/C41H46N4O10S/c1-41(2,3)26-19-34(39(51-5)36(20-26)56(6)49)45-40(48)44-33-11-12-35(32-10-8-7-9-31(32)33)55-28-13-14-42-37(24-28)43-27-21-29(50-4)23-30(22-27)54-18-17-52-15-16-53-25-38(46)47/h7-14,19-24H,15-18,25H2,1-6H3,(H,42,43)(H,46,47)(H2,44,45,48)
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n/an/a 8n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277694
PNG
(US10072034, Example 20(a) | US10072034, Example 20...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOC(C)C(O)=O)c1 |w:53.57|
Show InChI InChI=1S/C42H49N5O11S/c1-26(40(48)49)56-18-16-55-17-19-57-31-23-28(22-30(24-31)53-5)44-38-25-29(14-15-43-38)58-37-13-12-34(32-10-8-9-11-33(32)37)45-41(50)46-35-20-27(42(2,3)4)21-36(39(35)54-6)47-59(7,51)52/h8-15,20-26,47H,16-19H2,1-7H3,(H,43,44)(H,48,49)(H2,45,46,50)
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n/an/a 10.4n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277683
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(c4OC)S(C)(=O)=O)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(O)=O)c1
Show InChI InChI=1S/C41H46N4O11S/c1-41(2,3)26-19-34(39(52-5)36(20-26)57(6,49)50)45-40(48)44-33-11-12-35(32-10-8-7-9-31(32)33)56-28-13-14-42-37(24-28)43-27-21-29(51-4)23-30(22-27)55-18-17-53-15-16-54-25-38(46)47/h7-14,19-24H,15-18,25H2,1-6H3,(H,42,43)(H,46,47)(H2,44,45,48)
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n/an/a 11.7n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277685
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(N(C)S(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(O)=O)c1
Show InChI InChI=1S/C42H49N5O11S/c1-42(2,3)27-20-35(40(54-6)36(21-27)47(4)59(7,51)52)46-41(50)45-34-12-13-37(33-11-9-8-10-32(33)34)58-29-14-15-43-38(25-29)44-28-22-30(53-5)24-31(23-28)57-19-18-55-16-17-56-26-39(48)49/h8-15,20-25H,16-19,26H2,1-7H3,(H,43,44)(H,48,49)(H2,45,46,50)
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Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277696
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOC(C)(C)C(O)=O)c1
Show InChI InChI=1S/C43H51N5O11S/c1-42(2,3)27-21-35(39(55-7)36(22-27)48-60(8,52)53)47-41(51)46-34-13-14-37(33-12-10-9-11-32(33)34)59-29-15-16-44-38(26-29)45-28-23-30(54-6)25-31(24-28)57-19-17-56-18-20-58-43(4,5)40(49)50/h9-16,21-26,48H,17-20H2,1-8H3,(H,44,45)(H,49,50)(H2,46,47,51)
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n/an/a 14.4n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277701
PNG
(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCc2ccc(s2)C(O)=O)c1
Show InChI InChI=1S/C43H45N5O10S2/c1-43(2,3)26-19-35(40(55-5)36(20-26)48-60(6,52)53)47-42(51)46-34-12-13-37(33-10-8-7-9-32(33)34)58-28-15-16-44-39(24-28)45-27-21-29(54-4)23-30(22-27)57-18-17-56-25-31-11-14-38(59-31)41(49)50/h7-16,19-24,48H,17-18,25H2,1-6H3,(H,44,45)(H,49,50)(H2,46,47,51)
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Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277690
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(ethylsulf...)
Show SMILES CCS(=O)(=O)Nc1cc(cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(OC)cc(OCCOCCOCC(O)=O)c4)c3)c3ccccc23)c1OC)C(C)(C)C
Show InChI InChI=1S/C42H49N5O11S/c1-7-59(51,52)47-36-21-27(42(2,3)4)20-35(40(36)54-6)46-41(50)45-34-12-13-37(33-11-9-8-10-32(33)34)58-29-14-15-43-38(25-29)44-28-22-30(53-5)24-31(23-28)57-19-18-55-16-17-56-26-39(48)49/h8-15,20-25,47H,7,16-19,26H2,1-6H3,(H,43,44)(H,48,49)(H2,45,46,50)
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Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277689
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-3-(ethylsulfo...)
Show SMILES CCS(=O)(=O)c1cc(cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(OC)cc(OCCOCCOCC(O)=O)c4)c3)c3ccccc23)c1OC)C(C)(C)C
Show InChI InChI=1S/C42H48N4O11S/c1-7-58(50,51)37-21-27(42(2,3)4)20-35(40(37)53-6)46-41(49)45-34-12-13-36(33-11-9-8-10-32(33)34)57-29-14-15-43-38(25-29)44-28-22-30(52-5)24-31(23-28)56-19-18-54-16-17-55-26-39(47)48/h8-15,20-25H,7,16-19,26H2,1-6H3,(H,43,44)(H,47,48)(H2,45,46,49)
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Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277691
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl) isoxazol-3-y...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(on4)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(O)=O)c1
Show InChI InChI=1S/C36H39N5O9/c1-36(2,3)31-21-33(41-50-31)40-35(44)39-29-9-10-30(28-8-6-5-7-27(28)29)49-24-11-12-37-32(20-24)38-23-17-25(45-4)19-26(18-23)48-16-15-46-13-14-47-22-34(42)43/h5-12,17-21H,13-16,22H2,1-4H3,(H,37,38)(H,42,43)(H2,39,40,41,44)
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Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277677
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(O)=O)c1
Show InChI InChI=1S/C41H47N5O11S/c1-41(2,3)26-19-34(39(53-5)35(20-26)46-58(6,50)51)45-40(49)44-33-11-12-36(32-10-8-7-9-31(32)33)57-28-13-14-42-37(24-28)43-27-21-29(52-4)23-30(22-27)56-18-17-54-15-16-55-25-38(47)48/h7-14,19-24,46H,15-18,25H2,1-6H3,(H,42,43)(H,47,48)(H2,44,45,49)
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n/an/a 17.3n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277697
PNG
(1-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCn2cc(cn2)C(O)=O)c1
Show InChI InChI=1S/C43H47N7O10S/c1-43(2,3)28-19-36(40(57-5)37(20-28)49-61(6,54)55)48-42(53)47-35-11-12-38(34-10-8-7-9-33(34)35)60-30-13-14-44-39(24-30)46-29-21-31(56-4)23-32(22-29)59-18-17-58-16-15-50-26-27(25-45-50)41(51)52/h7-14,19-26,49H,15-18H2,1-6H3,(H,44,46)(H,51,52)(H2,47,48,53)
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n/an/a 18.1n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277680
PNG
(2-(2-(2-(3-((4-((4-(3-(5-tert-Butyl-2-methoxy-3-(m...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(=O)NS(C)(=O)=O)c1
Show InChI InChI=1S/C42H50N6O12S2/c1-42(2,3)27-20-35(40(56-5)36(21-27)47-61(6,51)52)46-41(50)45-34-12-13-37(33-11-9-8-10-32(33)34)60-29-14-15-43-38(25-29)44-28-22-30(55-4)24-31(23-28)59-19-18-57-16-17-58-26-39(49)48-62(7,53)54/h8-15,20-25,47H,16-19,26H2,1-7H3,(H,43,44)(H,48,49)(H2,45,46,50)
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n/an/a 18.1n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277694
PNG
(US10072034, Example 20(a) | US10072034, Example 20...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOC(C)C(O)=O)c1 |w:53.57|
Show InChI InChI=1S/C42H49N5O11S/c1-26(40(48)49)56-18-16-55-17-19-57-31-23-28(22-30(24-31)53-5)44-38-25-29(14-15-43-38)58-37-13-12-34(32-10-8-9-11-33(32)37)45-41(50)46-35-20-27(42(2,3)4)21-36(39(35)54-6)47-59(7,51)52/h8-15,20-26,47H,16-19H2,1-7H3,(H,43,44)(H,48,49)(H2,45,46,50)
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n/an/a 19.1n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277679
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-(methoxy-d...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(C)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(O)=O)c1
Show InChI InChI=1S/C41H46N4O9/c1-26-19-27(41(2,3)4)20-35(39(26)50-6)45-40(48)44-34-11-12-36(33-10-8-7-9-32(33)34)54-29-13-14-42-37(24-29)43-28-21-30(49-5)23-31(22-28)53-18-17-51-15-16-52-25-38(46)47/h7-14,19-24H,15-18,25H2,1-6H3,(H,42,43)(H,46,47)(H2,44,45,48)
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n/an/a 19.5n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277703
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Show SMILES COc1c(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(OCCOCCOCC(O)=O)cc(OC(F)F)c4)c3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C
Show InChI InChI=1S/C41H45F2N5O11S/c1-41(2,3)25-18-33(38(54-4)34(19-25)48-60(5,52)53)47-40(51)46-32-10-11-35(31-9-7-6-8-30(31)32)58-27-12-13-44-36(23-27)45-26-20-28(22-29(21-26)59-39(42)43)57-17-16-55-14-15-56-24-37(49)50/h6-13,18-23,39,48H,14-17,24H2,1-5H3,(H,44,45)(H,49,50)(H2,46,47,51)
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n/an/a 20.6n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277681
PNG
(2-(2-(2-(3-(4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(...)
Show SMILES CNC(=O)c1cc(cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(OC)cc(OCCOCCOCC(O)=O)c4)c3)c3ccccc23)c1OC)C(C)(C)C
Show InChI InChI=1S/C42H47N5O10/c1-42(2,3)26-19-33(40(50)43-4)39(53-6)35(20-26)47-41(51)46-34-11-12-36(32-10-8-7-9-31(32)34)57-28-13-14-44-37(24-28)45-27-21-29(52-5)23-30(22-27)56-18-17-54-15-16-55-25-38(48)49/h7-14,19-24H,15-18,25H2,1-6H3,(H,43,50)(H,44,45)(H,48,49)(H2,46,47,51)
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n/an/a 20.8n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277676
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)n2)cc(OCCOCCOCC(O)=O)c1
Show InChI InChI=1S/C40H46N6O11S/c1-40(2,3)25-19-32(37(53-5)33(20-25)46-58(6,50)51)44-39(49)43-31-11-12-34(30-10-8-7-9-29(30)31)57-35-13-14-41-38(45-35)42-26-21-27(52-4)23-28(22-26)56-18-17-54-15-16-55-24-36(47)48/h7-14,19-23,46H,15-18,24H2,1-6H3,(H,47,48)(H,41,42,45)(H2,43,44,49)
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n/an/a 24.6n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277700
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(=O)NS(=O)(=O)N(C)C)c1
Show InChI InChI=1S/C43H53N7O12S2/c1-43(2,3)28-21-36(41(58-7)37(22-28)48-63(8,53)54)47-42(52)46-35-13-14-38(34-12-10-9-11-33(34)35)62-30-15-16-44-39(26-30)45-29-23-31(57-6)25-32(24-29)61-20-19-59-17-18-60-27-40(51)49-64(55,56)50(4)5/h9-16,21-26,48H,17-20,27H2,1-8H3,(H,44,45)(H,49,51)(H2,46,47,52)
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n/an/a 26.3n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277684
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(dimethylp...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(c4OC)P(C)(C)=O)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCC(O)=O)c1
Show InChI InChI=1S/C42H49N4O10P/c1-42(2,3)27-20-35(40(52-5)37(21-27)57(6,7)50)46-41(49)45-34-12-13-36(33-11-9-8-10-32(33)34)56-29-14-15-43-38(25-29)44-28-22-30(51-4)24-31(23-28)55-19-18-53-16-17-54-26-39(47)48/h8-15,20-25H,16-19,26H2,1-7H3,(H,43,44)(H,47,48)(H2,45,46,49)
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n/an/a 26.5n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277698
PNG
(N-(3-(3-(4-((2-((3-(2-(2-(1H-Tetrazol-5-yl)methoxy...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCc2nnn[nH]2)c1
Show InChI InChI=1S/C41H47N9O9S/c1-41(2,3)26-19-34(39(55-5)35(20-26)48-60(6,52)53)45-40(51)44-33-11-12-36(32-10-8-7-9-31(32)33)59-28-13-14-42-37(24-28)43-27-21-29(54-4)23-30(22-27)58-18-17-56-15-16-57-25-38-46-49-50-47-38/h7-14,19-24,48H,15-18,25H2,1-6H3,(H,42,43)(H2,44,45,51)(H,46,47,49,50)
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n/an/a 29.2n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277692
PNG
(N-(5-(tert-Butl-2-methoxy-3-(3-(4-((2-((3-methoxy-...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCc2cc(=O)o[nH]2)c1
Show InChI InChI=1S/C43H48N6O11S/c1-43(2,3)27-19-36(41(55-5)37(20-27)49-61(6,52)53)47-42(51)46-35-11-12-38(34-10-8-7-9-33(34)35)59-30-13-14-44-39(25-30)45-28-21-31(54-4)24-32(22-28)58-18-17-56-15-16-57-26-29-23-40(50)60-48-29/h7-14,19-25,48-49H,15-18,26H2,1-6H3,(H,44,45)(H2,46,47,51)
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Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277699
PNG
(2-(2-(3-((4-((4-(3-(5-(tert-Buty-2-methoxy-3-(meth...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCC(O)=O)c1
Show InChI InChI=1S/C39H43N5O10S/c1-39(2,3)24-17-32(37(51-5)33(18-24)44-55(6,48)49)43-38(47)42-31-11-12-34(30-10-8-7-9-29(30)31)54-26-13-14-40-35(22-26)41-25-19-27(50-4)21-28(20-25)53-16-15-52-23-36(45)46/h7-14,17-22,44H,15-16,23H2,1-6H3,(H,40,41)(H,45,46)(H2,42,43,47)
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n/an/a 61.9n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM277678
PNG
(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Show SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(c1)C(=O)NCCOCCOCC(O)=O
Show InChI InChI=1S/C42H48N6O11S/c1-42(2,3)27-21-34(39(56-5)35(22-27)48-60(6,53)54)47-41(52)46-33-11-12-36(32-10-8-7-9-31(32)33)59-29-13-14-43-37(24-29)45-28-19-26(20-30(23-28)55-4)40(51)44-15-16-57-17-18-58-25-38(49)50/h7-14,19-24,48H,15-18,25H2,1-6H3,(H,43,45)(H,44,51)(H,49,50)(H2,46,47,52)
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n/an/a 115n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...

US Patent US10072034 (2018)


BindingDB Entry DOI: 10.7270/Q2B85B49
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM59542
PNG
((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1c(N)nc2ccccc12
Show InChI InChI=1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)
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n/an/a 551n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM59542
PNG
((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1c(N)nc2ccccc12
Show InChI InChI=1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)
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n/an/a 596n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM65733
PNG
(3-methyl-8-nitro-7-(phenylmethyl)purine-2,6-dione ...)
Show SMILES Cn1c2nc(n(Cc3ccccc3)c2c(=O)[nH]c1=O)[N+]([O-])=O
Show InChI InChI=1S/C13H11N5O4/c1-16-10-9(11(19)15-13(16)20)17(12(14-10)18(21)22)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,15,19,20)
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n/an/a 1.31E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q28C9TP6
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM65733
PNG
(3-methyl-8-nitro-7-(phenylmethyl)purine-2,6-dione ...)
Show SMILES Cn1c2nc(n(Cc3ccccc3)c2c(=O)[nH]c1=O)[N+]([O-])=O
Show InChI InChI=1S/C13H11N5O4/c1-16-10-9(11(19)15-13(16)20)17(12(14-10)18(21)22)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,15,19,20)
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n/an/a 2.16E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM65731
PNG
(3-methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purin...)
Show SMILES CC(C)Sc1nc2n(C)c(=O)[nH]c(=O)c2n1Cc1ccccc1
Show InChI InChI=1S/C16H18N4O2S/c1-10(2)23-16-17-13-12(14(21)18-15(22)19(13)3)20(16)9-11-7-5-4-6-8-11/h4-8,10H,9H2,1-3H3,(H,18,21,22)
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n/an/a 3.31E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM49106
PNG
(7-[(E)-but-2-enyl]-3-methyl-8-(3-phenylpropylsulfa...)
Show SMILES C\C=C\Cn1c(SCCCc2ccccc2)nc2n(C)c(=O)[nH]c(=O)c12
Show InChI InChI=1S/C19H22N4O2S/c1-3-4-12-23-15-16(22(2)18(25)21-17(15)24)20-19(23)26-13-8-11-14-9-6-5-7-10-14/h3-7,9-10H,8,11-13H2,1-2H3,(H,21,24,25)/b4-3+
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n/an/a 3.43E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM65729
PNG
(3-methyl-7-pentyl-8-(2-phenylethylsulfanyl)purine-...)
Show SMILES CCCCCn1c(SCCc2ccccc2)nc2n(C)c(=O)[nH]c(=O)c12
Show InChI InChI=1S/C19H24N4O2S/c1-3-4-8-12-23-15-16(22(2)18(25)21-17(15)24)20-19(23)26-13-11-14-9-6-5-7-10-14/h5-7,9-10H,3-4,8,11-13H2,1-2H3,(H,21,24,25)
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n/an/a 4.10E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM62334
PNG
(1-[(4-chlorophenyl)methyl]-2-benzimidazolamine | 1...)
Show SMILES Nc1nc2ccccc2n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C14H12ClN3/c15-11-7-5-10(6-8-11)9-18-13-4-2-1-3-12(13)17-14(18)16/h1-8H,9H2,(H2,16,17)
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n/an/a 4.59E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q28C9TP6
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM62332
PNG
(1-[2-(4-chloranylphenoxy)ethyl]benzimidazol-2-amin...)
Show SMILES Nc1nc2ccccc2n1CCOc1ccc(Cl)cc1
Show InChI InChI=1S/C15H14ClN3O/c16-11-5-7-12(8-6-11)20-10-9-19-14-4-2-1-3-13(14)18-15(19)17/h1-8H,9-10H2,(H2,17,18)
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n/an/a 8.60E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM62334
PNG
(1-[(4-chlorophenyl)methyl]-2-benzimidazolamine | 1...)
Show SMILES Nc1nc2ccccc2n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C14H12ClN3/c15-11-7-5-10(6-8-11)9-18-13-4-2-1-3-12(13)17-14(18)16/h1-8H,9H2,(H2,16,17)
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n/an/a 1.21E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM62349
PNG
(MLS-0281326.0001 | N-[1-(4-chlorobenzyl)benzimidaz...)
Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-5-3-4-6-15(14)21(17)11-12-7-9-13(18)10-8-12/h3-10H,2,11H2,1H3,(H,19,20,22)
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n/an/a 1.32E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q28C9TP6
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM59542
PNG
((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1c(N)nc2ccccc12
Show InChI InChI=1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)
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n/an/a 1.73E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q28C9TP6
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM59542
PNG
((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1c(N)nc2ccccc12
Show InChI InChI=1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)
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n/an/a 1.88E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q28C9TP6
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM54447
PNG
((5E)-5-[[2-(trifluoromethyl)phenyl]hydrazinylidene...)
Show SMILES Oc1ccc(N=Nc2ccccc2C(F)(F)F)c2cccnc12 |w:6.6|
Show InChI InChI=1S/C16H10F3N3O/c17-16(18,19)11-5-1-2-6-13(11)22-21-12-7-8-14(23)15-10(12)4-3-9-20-15/h1-9,23H
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n/an/a 1.98E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q20Z71QR
More data for this
Ligand-Target Pair
Interleukin-8


(Homo sapiens (Human))		BDBM62334
PNG
(1-[(4-chlorophenyl)methyl]-2-benzimidazolamine | 1...)
Show SMILES Nc1nc2ccccc2n1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C14H12ClN3/c15-11-7-5-10(6-8-11)9-18-13-4-2-1-3-12(13)17-14(18)16/h1-8H,9H2,(H2,16,17)
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n/an/a 1.98E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24M930Q
More data for this
Ligand-Target Pair