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Compile Data Set for Download or QSAR

Found 235 hits with Last Name = 'amato' and Initial = 'g'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144618
PNG
(CHEMBL3758534)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)C(=O)C(F)(F)F
Show InChI InChI=1S/C24H20Cl3F3N4O2/c1-13-20(22(35)31-17-8-10-33(11-9-17)23(36)24(28,29)30)32-34(19-7-6-16(26)12-18(19)27)21(13)14-2-4-15(25)5-3-14/h2-7,12,17H,8-11H2,1H3,(H,31,35)
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1.90n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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6.20n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144619
PNG
(CHEMBL3759785)
Show SMILES CC(C)OC(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C26H27Cl3N4O3/c1-15(2)36-26(35)32-12-10-20(11-13-32)30-25(34)23-16(3)24(17-4-6-18(27)7-5-17)33(31-23)22-9-8-19(28)14-21(22)29/h4-9,14-15,20H,10-13H2,1-3H3,(H,30,34)
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6.40n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144614
PNG
(CHEMBL3758884)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C29H25Cl3N4O2/c1-18-26(28(37)33-23-13-15-35(16-14-23)29(38)20-5-3-2-4-6-20)34-36(25-12-11-22(31)17-24(25)32)27(18)19-7-9-21(30)10-8-19/h2-12,17,23H,13-16H2,1H3,(H,33,37)
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7.5n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144609
PNG
(CHEMBL3759222)
Show SMILES CCCOC(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C26H27Cl3N4O3/c1-3-14-36-26(35)32-12-10-20(11-13-32)30-25(34)23-16(2)24(17-4-6-18(27)7-5-17)33(31-23)22-9-8-19(28)15-21(22)29/h4-9,15,20H,3,10-14H2,1-2H3,(H,30,34)
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8.80n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144615
PNG
(CHEMBL3759255)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)C(=O)C1CCCC1
Show InChI InChI=1S/C28H29Cl3N4O2/c1-17-25(27(36)32-22-12-14-34(15-13-22)28(37)19-4-2-3-5-19)33-35(24-11-10-21(30)16-23(24)31)26(17)18-6-8-20(29)9-7-18/h6-11,16,19,22H,2-5,12-15H2,1H3,(H,32,36)
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9.20n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144612
PNG
(CHEMBL3759254)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)S(=O)(=O)CCC(F)(F)F
Show InChI InChI=1S/C25H24Cl3F3N4O3S/c1-15-22(24(36)32-19-8-11-34(12-9-19)39(37,38)13-10-25(29,30)31)33-35(21-7-6-18(27)14-20(21)28)23(15)16-2-4-17(26)5-3-16/h2-7,14,19H,8-13H2,1H3,(H,32,36)
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9.60n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144617
PNG
(CHEMBL3759440)
Show SMILES CCCCC(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H29Cl3N4O2/c1-3-4-5-24(35)33-14-12-21(13-15-33)31-27(36)25-17(2)26(18-6-8-19(28)9-7-18)34(32-25)23-11-10-20(29)16-22(23)30/h6-11,16,21H,3-5,12-15H2,1-2H3,(H,31,36)
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15n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144616
PNG
(CHEMBL3758338)
Show SMILES CC(C)CC(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H29Cl3N4O2/c1-16(2)14-24(35)33-12-10-21(11-13-33)31-27(36)25-17(3)26(18-4-6-19(28)7-5-18)34(32-25)23-9-8-20(29)15-22(23)30/h4-9,15-16,21H,10-14H2,1-3H3,(H,31,36)
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29n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144610
PNG
(CHEMBL3759228)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C28H25Cl3N4O3S/c1-18-26(28(36)32-22-13-15-34(16-14-22)39(37,38)23-5-3-2-4-6-23)33-35(25-12-11-21(30)17-24(25)31)27(18)19-7-9-20(29)10-8-19/h2-12,17,22H,13-16H2,1H3,(H,32,36)
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43n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144613
PNG
(CHEMBL3758753)
Show SMILES CCS(=O)(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H25Cl3N4O3S/c1-3-35(33,34)30-12-10-19(11-13-30)28-24(32)22-15(2)23(16-4-6-17(25)7-5-16)31(29-22)21-9-8-18(26)14-20(21)27/h4-9,14,19H,3,10-13H2,1-2H3,(H,28,32)
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44n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50144611
PNG
(CHEMBL3758491)
Show SMILES CC(C)CS(=O)(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C26H29Cl3N4O3S/c1-16(2)15-37(35,36)32-12-10-21(11-13-32)30-26(34)24-17(3)25(18-4-6-19(27)7-5-18)33(31-24)23-9-8-20(28)14-22(23)29/h4-9,14,16,21H,10-13,15H2,1-3H3,(H,30,34)
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44n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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313n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144618
PNG
(CHEMBL3758534)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)C(=O)C(F)(F)F
Show InChI InChI=1S/C24H20Cl3F3N4O2/c1-13-20(22(35)31-17-8-10-33(11-9-17)23(36)24(28,29)30)32-34(19-7-6-16(26)12-18(19)27)21(13)14-2-4-15(25)5-3-14/h2-7,12,17H,8-11H2,1H3,(H,31,35)
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1.04E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144609
PNG
(CHEMBL3759222)
Show SMILES CCCOC(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C26H27Cl3N4O3/c1-3-14-36-26(35)32-12-10-20(11-13-32)30-25(34)23-16(2)24(17-4-6-18(27)7-5-17)33(31-23)22-9-8-19(28)15-21(22)29/h4-9,15,20H,3,10-14H2,1-2H3,(H,30,34)
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1.55E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144614
PNG
(CHEMBL3758884)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C29H25Cl3N4O2/c1-18-26(28(37)33-23-13-15-35(16-14-23)29(38)20-5-3-2-4-6-20)34-36(25-12-11-22(31)17-24(25)32)27(18)19-7-9-21(30)10-8-19/h2-12,17,23H,13-16H2,1H3,(H,33,37)
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1.73E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144617
PNG
(CHEMBL3759440)
Show SMILES CCCCC(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H29Cl3N4O2/c1-3-4-5-24(35)33-14-12-21(13-15-33)31-27(36)25-17(2)26(18-6-8-19(28)9-7-18)34(32-25)23-11-10-20(29)16-22(23)30/h6-11,16,21H,3-5,12-15H2,1-2H3,(H,31,36)
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1.79E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144616
PNG
(CHEMBL3758338)
Show SMILES CC(C)CC(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H29Cl3N4O2/c1-16(2)14-24(35)33-12-10-21(11-13-33)31-27(36)25-17(3)26(18-4-6-19(28)7-5-18)34(32-25)23-9-8-20(29)15-22(23)30/h4-9,15-16,21H,10-14H2,1-3H3,(H,31,36)
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1.81E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144619
PNG
(CHEMBL3759785)
Show SMILES CC(C)OC(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C26H27Cl3N4O3/c1-15(2)36-26(35)32-12-10-20(11-13-32)30-25(34)23-16(3)24(17-4-6-18(27)7-5-17)33(31-23)22-9-8-19(28)14-21(22)29/h4-9,14-15,20H,10-13H2,1-3H3,(H,30,34)
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1.93E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144615
PNG
(CHEMBL3759255)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)C(=O)C1CCCC1
Show InChI InChI=1S/C28H29Cl3N4O2/c1-17-25(27(36)32-22-12-14-34(15-13-22)28(37)19-4-2-3-5-19)33-35(24-11-10-21(30)16-23(24)31)26(17)18-6-8-20(29)9-7-18/h6-11,16,19,22H,2-5,12-15H2,1H3,(H,32,36)
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2.50E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144613
PNG
(CHEMBL3758753)
Show SMILES CCS(=O)(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H25Cl3N4O3S/c1-3-35(33,34)30-12-10-19(11-13-30)28-24(32)22-15(2)23(16-4-6-17(25)7-5-16)31(29-22)21-9-8-18(26)14-20(21)27/h4-9,14,19H,3,10-13H2,1-2H3,(H,28,32)
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4.41E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144612
PNG
(CHEMBL3759254)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)S(=O)(=O)CCC(F)(F)F
Show InChI InChI=1S/C25H24Cl3F3N4O3S/c1-15-22(24(36)32-19-8-11-34(12-9-19)39(37,38)13-10-25(29,30)31)33-35(21-7-6-18(27)14-20(21)28)23(15)16-2-4-17(26)5-3-16/h2-7,14,19H,8-13H2,1H3,(H,32,36)
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4.72E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144611
PNG
(CHEMBL3758491)
Show SMILES CC(C)CS(=O)(=O)N1CCC(CC1)NC(=O)c1nn(c(c1C)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C26H29Cl3N4O3S/c1-16(2)15-37(35,36)32-12-10-21(11-13-32)30-26(34)24-17(3)25(18-4-6-19(27)7-5-18)33(31-24)23-9-8-20(28)14-22(23)29/h4-9,14,16,21H,10-13,15H2,1-3H3,(H,30,34)
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6.21E+3n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50144610
PNG
(CHEMBL3759228)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NC1CCN(CC1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C28H25Cl3N4O3S/c1-18-26(28(36)32-22-13-15-34(16-14-22)39(37,38)23-5-3-2-4-6-23)33-35(25-12-11-21(30)17-24(25)31)27(18)19-7-9-20(29)10-8-19/h2-12,17,22H,13-16H2,1H3,(H,32,36)
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>2.00E+4n/an/an/an/an/an/an/an/a



RTI International

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes


Bioorg Med Chem 24: 1063-70 (2016)


BindingDB Entry DOI: 10.7270/Q2GB25WW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4091459
PNG
KEGG

UniProtKB/SwissProt

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n/an/a 8n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4095993
PNG
KEGG

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
n/an/a 9n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4098431
PNG
KEGG

UniProtKB/SwissProt

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PC cid
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UniChem
n/an/a 9n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4062193
PNG
KEGG

UniProtKB/SwissProt

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n/an/a 11n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4062193
PNG
KEGG

UniProtKB/SwissProt

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n/an/a 11n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4062193
PNG
PDB

KEGG

UniProtKB/SwissProt

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n/an/a 20n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4103611
PNG
KEGG

UniProtKB/SwissProt

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n/an/a 23n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50099581
PNG
(CHEMBL288131 | N-((2R,3R)-3-(4-ethylphenylsulfonam...)
Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)Cc2ccc(NC(=O)c3cccc(OC)c3)cc12 |r|
Show InChI InChI=1S/C25H26N2O5S/c1-3-16-7-11-21(12-8-16)33(30,31)27-24-22-15-19(10-9-17(22)14-23(24)28)26-25(29)18-5-4-6-20(13-18)32-2/h4-13,15,23-24,27-28H,3,14H2,1-2H3,(H,26,29)/t23-,24-/m1/s1
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n/an/a 33n/an/an/an/an/an/a



Icagen Inc.

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5 channel mediated delayed rectifier potassium current by patch-clamp technique


Bioorg Med Chem Lett 17: 2849-53 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.052
BindingDB Entry DOI: 10.7270/Q2VM4BZS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4103611
PNG
PDB

KEGG

UniProtKB/SwissProt

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UniChem
n/an/a 38n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4095993
PNG
PDB

KEGG

UniProtKB/SwissProt

DrugBank
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UniChem
n/an/a 42n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4088258
PNG
KEGG

UniProtKB/SwissProt

GoogleScholar
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PC cid
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UniChem
n/an/a 49n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4098431
PNG
PDB

KEGG

UniProtKB/SwissProt

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n/an/a 53n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4063630
PNG
PDB

KEGG

UniProtKB/SwissProt

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n/an/a 74n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4063630
PNG
KEGG

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
n/an/a 80n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4091459
PNG
PDB

KEGG

UniProtKB/SwissProt

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n/an/a 91n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4060024
PNG
KEGG

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4088258
PNG
PDB

KEGG

UniProtKB/SwissProt

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n/an/a 111n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4100238
PNG
KEGG

UniProtKB/SwissProt

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n/an/a 116n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4073272
PNG
KEGG

UniProtKB/SwissProt

GoogleScholar
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UniChem
n/an/a 128n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4060024
PNG
PDB

KEGG

UniProtKB/SwissProt

DrugBank
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UniChem
n/an/a 131n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
CHEMBL4073272
PNG
PDB

KEGG

UniProtKB/SwissProt

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n/an/a 134n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50207909
PNG
(CHEMBL239805 | N-(3-(4-ethylphenylsulfonamido)-2,3...)
Show SMILES CCc1ccc(cc1)S(=O)(=O)NC1CCc2ccc(NC(=O)c3cccc(OC)c3)cc12 |w:12.12|
Show InChI InChI=1S/C25H26N2O4S/c1-3-17-7-12-22(13-8-17)32(29,30)27-24-14-10-18-9-11-20(16-23(18)24)26-25(28)19-5-4-6-21(15-19)31-2/h4-9,11-13,15-16,24,27H,3,10,14H2,1-2H3,(H,26,28)
PDB

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n/an/a 150n/an/an/an/an/an/a



Icagen Inc.

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5 channel mediated delayed rectifier potassium current by patch-clamp technique


Bioorg Med Chem Lett 17: 2849-53 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.052
BindingDB Entry DOI: 10.7270/Q2VM4BZS
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50099581
PNG
(CHEMBL288131 | N-((2R,3R)-3-(4-ethylphenylsulfonam...)
Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)Cc2ccc(NC(=O)c3cccc(OC)c3)cc12 |r|
Show InChI InChI=1S/C25H26N2O5S/c1-3-16-7-11-21(12-8-16)33(30,31)27-24-22-15-19(10-9-17(22)14-23(24)28)26-25(29)18-5-4-6-20(13-18)32-2/h4-13,15,23-24,27-28H,3,14H2,1-2H3,(H,26,29)/t23-,24-/m1/s1
PDB

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n/an/a 160n/an/an/an/an/an/a



Icagen Inc.

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5 channel mediated delayed rectifier potassium current by patch-clamp technique


Bioorg Med Chem Lett 17: 2849-53 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.052
BindingDB Entry DOI: 10.7270/Q2VM4BZS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4101680
PNG
KEGG

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
n/an/a 195n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50207912
PNG
(CHEMBL239808 | N-((8R,9R)-9-(4-ethylphenylsulfonam...)
Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)CCCc2ccc(NC(=O)c3cccc(OC)c3)cc12
Show InChI InChI=1S/C27H30N2O5S/c1-3-18-10-14-23(15-11-18)35(32,33)29-26-24-17-21(13-12-19(24)6-5-9-25(26)30)28-27(31)20-7-4-8-22(16-20)34-2/h4,7-8,10-17,25-26,29-30H,3,5-6,9H2,1-2H3,(H,28,31)/t25-,26-/m1/s1
PDB

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n/an/a 200n/an/an/an/an/an/a



Icagen Inc.

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5 channel mediated delayed rectifier potassium current by patch-clamp technique


Bioorg Med Chem Lett 17: 2849-53 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.052
BindingDB Entry DOI: 10.7270/Q2VM4BZS
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
CHEMBL4067095
PNG
KEGG

UniProtKB/SwissProt

GoogleScholar
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PC cid
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UniChem

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n/an/a 216n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
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