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Compile Data Set for Download or QSAR

Found 59 hits with Last Name = 'bassani' and Initial = 'f'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208047
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O/c1-31(19-17-23-11-5-2-6-12-23)20-18-26(21-31)30-22-28(29-27(30)32,24-13-7-3-8-14-24)25-15-9-4-10-16-25/h2-16,26H,17-22H2,1H3/p+1
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0.670n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208057
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCCc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H33N3O/c1-32(20-11-14-24-12-5-2-6-13-24)21-19-27(22-32)31-23-29(30-28(31)33,25-15-7-3-8-16-25)26-17-9-4-10-18-26/h2-10,12-13,15-18,27H,11,14,19-23H2,1H3/p+1
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0.700n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208057
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCCc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H33N3O/c1-32(20-11-14-24-12-5-2-6-13-24)21-19-27(22-32)31-23-29(30-28(31)33,25-15-7-3-8-16-25)26-17-9-4-10-18-26/h2-10,12-13,15-18,27H,11,14,19-23H2,1H3/p+1
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0.730n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208043
PNG
(1-methyl-3-(R)-[4,4-Bis-(4-fluoro-phenyl)-2-oxo-im...)
Show SMILES C[N+]1(CCc2ccccc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C28H29F2N3O/c1-33(17-15-21-5-3-2-4-6-21)18-16-26(19-33)32-20-28(31-27(32)34,22-7-11-24(29)12-8-22)23-9-13-25(30)14-10-23/h2-14,26H,15-20H2,1H3/p+1/t26-,33?/m1/s1
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0.75n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208044
PNG
(1-methyl-3-(R)-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(CCOc2ccccc2)CC[C@H](C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O2/c1-31(19-20-33-26-15-9-4-10-16-26)18-17-25(21-31)30-22-28(29-27(30)32,23-11-5-2-6-12-23)24-13-7-3-8-14-24/h2-16,25H,17-22H2,1H3/p+1/t25-,31?/m1/s1
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1.04n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208035
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2ccsc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C26H25F2N3O2S/c1-31(15-24(32)18-11-13-34-16-18)12-10-23(14-31)30-17-26(29-25(30)33,19-2-6-21(27)7-3-19)20-4-8-22(28)9-5-20/h2-9,11,13,16,23H,10,12,14-15,17H2,1H3/p+1/t23-,31?/m1/s1
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1.62n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208038
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCOc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O2/c1-31(19-20-33-26-15-9-4-10-16-26)18-17-25(21-31)30-22-28(29-27(30)32,23-11-5-2-6-12-23)24-13-7-3-8-14-24/h2-16,25H,17-22H2,1H3/p+1
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1.66n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208056
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCCOc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H33N3O2/c1-32(19-11-21-34-27-16-9-4-10-17-27)20-18-26(22-32)31-23-29(30-28(31)33,24-12-5-2-6-13-24)25-14-7-3-8-15-25/h2-10,12-17,26H,11,18-23H2,1H3/p+1
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1.76n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208051
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2ccccc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C28H27F2N3O2/c1-33(18-26(34)20-5-3-2-4-6-20)16-15-25(17-33)32-19-28(31-27(32)35,21-7-11-23(29)12-8-21)22-9-13-24(30)14-10-22/h2-14,25H,15-19H2,1H3/p+1/t25-,33?/m1/s1
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1.84n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208058
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CC(=O)c2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H29N3O2/c1-31(20-26(32)22-11-5-2-6-12-22)18-17-25(19-31)30-21-28(29-27(30)33,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-16,25H,17-21H2,1H3/p+1
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1.89n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208038
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCOc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O2/c1-31(19-20-33-26-15-9-4-10-16-26)18-17-25(21-31)30-22-28(29-27(30)32,23-11-5-2-6-12-23)24-13-7-3-8-14-24/h2-16,25H,17-22H2,1H3/p+1
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1.89n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208044
PNG
(1-methyl-3-(R)-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(CCOc2ccccc2)CC[C@H](C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O2/c1-31(19-20-33-26-15-9-4-10-16-26)18-17-25(21-31)30-22-28(29-27(30)32,23-11-5-2-6-12-23)24-13-7-3-8-14-24/h2-16,25H,17-22H2,1H3/p+1/t25-,31?/m1/s1
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2.39n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208041
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2ccccn2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H26F2N4O2/c1-33(17-25(34)24-4-2-3-14-30-24)15-13-23(16-33)32-18-27(31-26(32)35,19-5-9-21(28)10-6-19)20-7-11-22(29)12-8-20/h2-12,14,23H,13,15-18H2,1H3/p+1/t23-,33?/m1/s1
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2.61n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208029
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2cccc(F)c2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C28H26F3N3O2/c1-34(17-26(35)19-3-2-4-24(31)15-19)14-13-25(16-34)33-18-28(32-27(33)36,20-5-9-22(29)10-6-20)21-7-11-23(30)12-8-21/h2-12,15,25H,13-14,16-18H2,1H3/p+1/t25-,34?/m1/s1
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3.01n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208047
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O/c1-31(19-17-23-11-5-2-6-12-23)20-18-26(21-31)30-22-28(29-27(30)32,24-13-7-3-8-14-24)25-15-9-4-10-16-25/h2-16,26H,17-22H2,1H3/p+1
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5.40n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208036
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(C[C@H]2O[C@@H]2c2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31N3O2/c1-32(20-26-27(34-26)22-11-5-2-6-12-22)18-17-25(19-32)31-21-29(30-28(31)33,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-16,25-27H,17-21H2,1H3/p+1/t25?,26-,27-,32?/m1/s1
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6.66n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208039
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCOCc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H33N3O2/c1-32(19-20-34-22-24-11-5-2-6-12-24)18-17-27(21-32)31-23-29(30-28(31)33,25-13-7-3-8-14-25)26-15-9-4-10-16-26/h2-16,27H,17-23H2,1H3/p+1
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6.70n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208054
PNG
(1-methyl-3-(S)-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(CCOc2ccccc2)CC[C@@H](C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O2/c1-31(19-20-33-26-15-9-4-10-16-26)18-17-25(21-31)30-22-28(29-27(30)32,23-11-5-2-6-12-23)24-13-7-3-8-14-24/h2-16,25H,17-22H2,1H3/p+1/t25-,31?/m0/s1
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7.60n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208056
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCCOc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H33N3O2/c1-32(19-11-21-34-27-16-9-4-10-17-27)20-18-26(22-32)31-23-29(30-28(31)33,24-12-5-2-6-13-24)25-14-7-3-8-15-25/h2-10,12-17,26H,11,18-23H2,1H3/p+1
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8.84n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208034
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CC(=O)Nc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H30N4O2/c1-32(20-26(33)29-24-15-9-4-10-16-24)18-17-25(19-32)31-21-28(30-27(31)34,22-11-5-2-6-12-22)23-13-7-3-8-14-23/h2-16,25H,17-21H2,1H3,(H-,29,30,33,34)/p+1
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9.11n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208034
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CC(=O)Nc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H30N4O2/c1-32(20-26(33)29-24-15-9-4-10-16-24)18-17-25(19-32)31-21-28(30-27(31)34,22-11-5-2-6-12-22)23-13-7-3-8-14-23/h2-16,25H,17-21H2,1H3,(H-,29,30,33,34)/p+1
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9.92n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208043
PNG
(1-methyl-3-(R)-[4,4-Bis-(4-fluoro-phenyl)-2-oxo-im...)
Show SMILES C[N+]1(CCc2ccccc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C28H29F2N3O/c1-33(17-15-21-5-3-2-4-6-21)18-16-26(19-33)32-20-28(31-27(32)34,22-7-11-24(29)12-8-22)23-9-13-25(30)14-10-23/h2-14,26H,15-20H2,1H3/p+1/t26-,33?/m1/s1
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21.9n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208046
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2cccnc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H26F2N4O2/c1-33(17-25(34)19-3-2-13-30-15-19)14-12-24(16-33)32-18-27(31-26(32)35,20-4-8-22(28)9-5-20)21-6-10-23(29)11-7-21/h2-11,13,15,24H,12,14,16-18H2,1H3/p+1/t24-,33?/m1/s1
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22.9n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208036
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(C[C@H]2O[C@@H]2c2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31N3O2/c1-32(20-26-27(34-26)22-11-5-2-6-12-22)18-17-25(19-32)31-21-29(30-28(31)33,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-16,25-27H,17-21H2,1H3/p+1/t25?,26-,27-,32?/m1/s1
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27.4n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208058
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CC(=O)c2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H29N3O2/c1-31(20-26(32)22-11-5-2-6-12-22)18-17-25(19-31)30-21-28(29-27(30)33,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-16,25H,17-21H2,1H3/p+1
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31.5n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208039
PNG
(1-methyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-...)
Show SMILES C[N+]1(CCOCc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H33N3O2/c1-32(19-20-34-22-24-11-5-2-6-12-24)18-17-27(21-32)31-23-29(30-28(31)33,25-13-7-3-8-14-25)26-15-9-4-10-16-26/h2-16,27H,17-23H2,1H3/p+1
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47.8n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208035
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2ccsc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C26H25F2N3O2S/c1-31(15-24(32)18-11-13-34-16-18)12-10-23(14-31)30-17-26(29-25(30)33,19-2-6-21(27)7-3-19)20-4-8-22(28)9-5-20/h2-9,11,13,16,23H,10,12,14-15,17H2,1H3/p+1/t23-,31?/m1/s1
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88.5n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208051
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2ccccc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C28H27F2N3O2/c1-33(18-26(34)20-5-3-2-4-6-20)16-15-25(17-33)32-19-28(31-27(32)35,21-7-11-23(29)12-8-21)22-9-13-24(30)14-10-22/h2-14,25H,15-19H2,1H3/p+1/t25-,33?/m1/s1
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94.5n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208029
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2cccc(F)c2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C28H26F3N3O2/c1-34(17-26(35)19-3-2-4-24(31)15-19)14-13-25(16-34)33-18-28(32-27(33)36,20-5-9-22(29)10-6-20)21-7-11-23(30)12-8-21/h2-12,15,25H,13-14,16-18H2,1H3/p+1/t25-,34?/m1/s1
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108n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208050
PNG
(8,8-dimethyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(C)C2CCC1CC(C2)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H29N3O/c1-27(2)21-13-14-22(27)16-20(15-21)26-17-24(25-23(26)28,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-22H,13-17H2,1-2H3/p+1
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153n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208054
PNG
(1-methyl-3-(S)-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(CCOc2ccccc2)CC[C@@H](C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C28H31N3O2/c1-31(19-20-33-26-15-9-4-10-16-26)18-17-25(21-31)30-22-28(29-27(30)32,23-11-5-2-6-12-23)24-13-7-3-8-14-24/h2-16,25H,17-22H2,1H3/p+1/t25-,31?/m0/s1
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157n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208045
PNG
(1,1-dimethyl-4-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(C)CCC(CC1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H27N3O/c1-25(2)15-13-20(14-16-25)24-17-22(23-21(24)26,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20H,13-17H2,1-2H3/p+1
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249n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208041
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2ccccn2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H26F2N4O2/c1-33(17-25(34)24-4-2-3-14-30-24)15-13-23(16-33)32-18-27(31-26(32)35,19-5-9-21(28)10-6-19)20-7-11-22(29)12-8-20/h2-12,14,23H,13,15-18H2,1H3/p+1/t23-,33?/m1/s1
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268n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208037
PNG
(1-methyl-3-(R)-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(Cc2ccccc2)CC[C@H](C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H29N3O/c1-30(19-22-11-5-2-6-12-22)18-17-25(20-30)29-21-27(28-26(29)31,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-16,25H,17-21H2,1H3/p+1/t25-,30?/m1/s1
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282n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208030
PNG
(1,1-dimethyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(C)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C21H25N3O/c1-24(2)14-13-19(15-24)23-16-21(22-20(23)25,17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,19H,13-16H2,1-2H3/p+1
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310n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208032
PNG
(CHEMBL224784 | trimethyl-[2-(2-oxo-4,4-diphenyl-im...)
Show SMILES C[N+](C)(C)CCN1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C20H25N3O/c1-23(2,3)15-14-22-16-20(21-19(22)24,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-13H,14-16H2,1-3H3/p+1
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335n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208031
PNG
(1-methoxyethyl-3-(2-oxo-4,4-diphenyl-imidazolidin-...)
Show SMILES COCC[N+]1(CCOc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H35N3O3/c1-35-21-19-33(20-22-36-28-15-9-4-10-16-28)18-17-27(23-33)32-24-30(31-29(32)34,25-11-5-2-6-12-25)26-13-7-3-8-14-26/h2-16,27H,17-24H2,1H3/p+1
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356n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208050
PNG
(8,8-dimethyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(C)C2CCC1CC(C2)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H29N3O/c1-27(2)21-13-14-22(27)16-20(15-21)26-17-24(25-23(26)28,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20-22H,13-17H2,1-2H3/p+1
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498n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208055
PNG
(CHEMBL222426 | benzyl-dimethyl-[2-(2-oxo-4,4-diphe...)
Show SMILES C[N+](C)(CCN1CC(NC1=O)(c1ccccc1)c1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C26H29N3O/c1-29(2,20-22-12-6-3-7-13-22)19-18-28-21-26(27-25(28)30,23-14-8-4-9-15-23)24-16-10-5-11-17-24/h3-17H,18-21H2,1-2H3/p+1
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507n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208033
PNG
(1-cyanomethyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1...)
Show SMILES O=C1NC(CN1C1CC[N+](CCOc2ccccc2)(CC#N)C1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H30N4O2/c30-17-19-33(20-21-35-27-14-8-3-9-15-27)18-16-26(22-33)32-23-29(31-28(32)34,24-10-4-1-5-11-24)25-12-6-2-7-13-25/h1-15,26H,16,18-23H2/p+1
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541n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208031
PNG
(1-methoxyethyl-3-(2-oxo-4,4-diphenyl-imidazolidin-...)
Show SMILES COCC[N+]1(CCOc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H35N3O3/c1-35-21-19-33(20-22-36-28-15-9-4-10-16-28)18-17-27(23-33)32-24-30(31-29(32)34,25-11-5-2-6-12-25)26-13-7-3-8-14-26/h2-16,27H,17-24H2,1H3/p+1
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552n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208052
PNG
(1-benzyl-1-methyl-4-(2-oxo-4,4-diphenyl-imidazolid...)
Show SMILES C[N+]1(Cc2ccccc2)CCC(CC1)N1CC(NC1=O)(c1ccccc1)c1ccccc1 |(1.29,2.89,;.49,4.2,;1.57,5.3,;3.07,4.97,;3.54,3.51,;5.04,3.17,;6.08,4.31,;5.6,5.78,;4.1,6.11,;.16,2.7,;-1.3,2.23,;-2.45,3.26,;-2.12,4.77,;-.65,5.24,;-3.91,2.78,;-4.39,1.32,;-5.93,1.32,;-6.4,2.78,;-5.16,3.69,;-5.16,5.23,;-5.22,-.04,;-6.06,-1.34,;-5.35,-2.7,;-3.81,-2.77,;-2.98,-1.46,;-3.7,-.1,;-7.48,1.32,;-8.25,2.67,;-9.79,2.67,;-10.57,1.33,;-9.79,-.02,;-8.24,-.01,)|
Show InChI InChI=1S/C28H31N3O/c1-31(21-23-11-5-2-6-12-23)19-17-26(18-20-31)30-22-28(29-27(30)32,24-13-7-3-8-14-24)25-15-9-4-10-16-25/h2-16,26H,17-22H2,1H3/p+1
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612n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208042
PNG
(CHEMBL225332 | benzyl-dimethyl-[3-(2-oxo-4,4-diphe...)
Show SMILES C[N+](C)(CCCN1CC(NC1=O)(c1ccccc1)c1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C27H31N3O/c1-30(2,21-23-13-6-3-7-14-23)20-12-19-29-22-27(28-26(29)31,24-15-8-4-9-16-24)25-17-10-5-11-18-25/h3-11,13-18H,12,19-22H2,1-2H3/p+1
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619n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208053
PNG
(1-benzyl-1-methyl-3-(2-oxo-4,4-diphenyl-imidazolid...)
Show SMILES C[N+]1(Cc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H29N3O/c1-30(19-22-11-5-2-6-12-22)18-17-25(20-30)29-21-27(28-26(29)31,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-16,25H,17-21H2,1H3/p+1
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727n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208030
PNG
(1,1-dimethyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(C)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C21H25N3O/c1-24(2)14-13-19(15-24)23-16-21(22-20(23)25,17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,19H,13-16H2,1-2H3/p+1
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862n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208037
PNG
(1-methyl-3-(R)-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(Cc2ccccc2)CC[C@H](C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H29N3O/c1-30(19-22-11-5-2-6-12-22)18-17-25(20-30)29-21-27(28-26(29)31,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-16,25H,17-21H2,1H3/p+1/t25-,30?/m1/s1
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884n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208046
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2cccnc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H26F2N4O2/c1-33(17-25(34)19-3-2-13-30-15-19)14-12-24(16-33)32-18-27(31-26(32)35,20-4-8-22(28)9-5-20)21-6-10-23(29)11-7-21/h2-11,13,15,24H,12,14,16-18H2,1H3/p+1/t24-,33?/m1/s1
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1.01E+3n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208033
PNG
(1-cyanomethyl-3-(2-oxo-4,4-diphenyl-imidazolidin-1...)
Show SMILES O=C1NC(CN1C1CC[N+](CCOc2ccccc2)(CC#N)C1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H30N4O2/c30-17-19-33(20-21-35-27-14-8-3-9-15-27)18-16-26(22-33)32-23-29(31-28(32)34,24-10-4-1-5-11-24)25-12-6-2-7-13-25/h1-15,26H,16,18-23H2/p+1
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1.15E+3n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208045
PNG
(1,1-dimethyl-4-(2-oxo-4,4-diphenyl-imidazolidin-1-...)
Show SMILES C[N+]1(C)CCC(CC1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H27N3O/c1-25(2)15-13-20(14-16-25)24-17-22(23-21(24)26,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,20H,13-17H2,1-2H3/p+1
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1.81E+3n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208053
PNG
(1-benzyl-1-methyl-3-(2-oxo-4,4-diphenyl-imidazolid...)
Show SMILES C[N+]1(Cc2ccccc2)CCC(C1)N1CC(NC1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H29N3O/c1-30(19-22-11-5-2-6-12-22)18-17-25(20-30)29-21-27(28-26(29)31,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-16,25H,17-21H2,1H3/p+1
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2.01E+3n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
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