new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 71 hits with Last Name = 'bienfait' and Initial = 'b'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50057512
PNG
((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Show SMILES CCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(=O)CCC |c:23,t:12|
Show InChI InChI=1S/C28H40O8/c1-7-9-20(30)35-24-16(4)27(34)18(22-25(5,6)28(22,24)36-21(31)10-8-2)12-17(14-29)13-26(33)19(27)11-15(3)23(26)32/h11-12,16,18-19,22,24,29,33-34H,7-10,13-14H2,1-6H3/t16-,18+,19-,22?,24-,26-,27-,28-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

PubMed
0.200n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091249
PNG
(CHEMBL108303 | Nonanoic acid 2-hydroxy-1-(4-nonyli...)
Show SMILES CCCCCCCC\C=C1/CC(OC1=O)[C@H](CO)OC(=O)CCCCCCCC
Show InChI InChI=1S/C24H42O5/c1-3-5-7-9-11-12-14-16-20-18-21(29-24(20)27)22(19-25)28-23(26)17-15-13-10-8-6-4-2/h16,21-22,25H,3-15,17-19H2,1-2H3/b20-16+/t21?,22-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
1.20n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase C alpha


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091254
PNG
(CHEMBL109630 | Nonanoic acid (S)-2-hydroxy-1-(4-no...)
Show SMILES CCCCCCCC\C=C1\CC(OC1=O)[C@H](CO)OC(=O)CCCCCCCC
Show InChI InChI=1S/C24H42O5/c1-3-5-7-9-11-12-14-16-20-18-21(29-24(20)27)22(19-25)28-23(26)17-15-13-10-8-6-4-2/h16,21-22,25H,3-15,17-19H2,1-2H3/b20-16-/t21?,22-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
1.80n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase C alpha


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085889
PNG
(CHEMBL111625 | Decanoic acid 2-hydroxymethyl-4-(3-...)
Show SMILES CCCCCCCCCC(=O)OCC1(CO)C\C(=C\CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C25H44O5/c1-6-7-8-9-10-11-12-13-23(27)29-18-25(17-26)16-21(24(28)30-25)14-15-22(19(2)3)20(4)5/h14,19-20,22,26H,6-13,15-18H2,1-5H3/b21-14-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
2.30n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase-C alpha (PK-C alpha)


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091247
PNG
(CHEMBL110779 | Decanoic acid 2-hydroxymethyl-4-(3-...)
Show SMILES CCCCCCCCCC(=O)OCC1(CO)C\C(=C\CC(C)C)C(=O)O1
Show InChI InChI=1S/C21H36O5/c1-4-5-6-7-8-9-10-11-19(23)25-16-21(15-22)14-18(20(24)26-21)13-12-17(2)3/h13,17,22H,4-12,14-16H2,1-3H3/b18-13-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
2.30n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase C alpha


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085889
PNG
(CHEMBL111625 | Decanoic acid 2-hydroxymethyl-4-(3-...)
Show SMILES CCCCCCCCCC(=O)OCC1(CO)C\C(=C\CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C25H44O5/c1-6-7-8-9-10-11-12-13-23(27)29-18-25(17-26)16-21(24(28)30-25)14-15-22(19(2)3)20(4)5/h14,19-20,22,26H,6-13,15-18H2,1-5H3/b21-14-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
2.30n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085880
PNG
(3-Isopropyl-4-methyl-pentanoic acid 2-hydroxymethy...)
Show SMILES CC(C)C(C\C=C1/CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O)C(C)C
Show InChI InChI=1S/C24H42O5/c1-15(2)20(16(3)4)10-9-19-12-24(13-25,29-23(19)27)14-28-22(26)11-21(17(5)6)18(7)8/h9,15-18,20-21,25H,10-14H2,1-8H3/b19-9+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
2.70n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085904
PNG
(3-Isopropyl-4-methyl-pentanoic acid 2-hydroxymethy...)
Show SMILES CC(C)C(C\C=C1\CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O)C(C)C
Show InChI InChI=1S/C24H42O5/c1-15(2)20(16(3)4)10-9-19-12-24(13-25,29-23(19)27)14-28-22(26)11-21(17(5)6)18(7)8/h9,15-18,20-21,25H,10-14H2,1-8H3/b19-9-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
2.90n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Displacement of [20-3H] phorbol 12,13-dibutyrate from protein kinase C alpha


Bioorg Med Chem Lett 10: 653-5 (2000)


BindingDB Entry DOI: 10.7270/Q2G16011
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085904
PNG
(3-Isopropyl-4-methyl-pentanoic acid 2-hydroxymethy...)
Show SMILES CC(C)C(C\C=C1\CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O)C(C)C
Show InChI InChI=1S/C24H42O5/c1-15(2)20(16(3)4)10-9-19-12-24(13-25,29-23(19)27)14-28-22(26)11-21(17(5)6)18(7)8/h9,15-18,20-21,25H,10-14H2,1-8H3/b19-9-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
2.90n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091245
PNG
(3-Methyl-butyric acid 2-hydroxymethyl-4-(3-methyl-...)
Show SMILES CC(C)C\C=C1\CC(CO)(COC(=O)CC(C)C)OC1=O
Show InChI InChI=1S/C16H26O5/c1-11(2)5-6-13-8-16(9-17,21-15(13)19)10-20-14(18)7-12(3)4/h6,11-12,17H,5,7-10H2,1-4H3/b13-6-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
2.90n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase C alpha


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085904
PNG
(3-Isopropyl-4-methyl-pentanoic acid 2-hydroxymethy...)
Show SMILES CC(C)C(C\C=C1\CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O)C(C)C
Show InChI InChI=1S/C24H42O5/c1-15(2)20(16(3)4)10-9-19-12-24(13-25,29-23(19)27)14-28-22(26)11-21(17(5)6)18(7)8/h9,15-18,20-21,25H,10-14H2,1-8H3/b19-9-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
2.90n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase-C alpha (PK-C alpha)


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085881
PNG
(3-[2-Hydroxymethyl-4-(3-isopropyl-4-methyl-pentyli...)
Show SMILES CCCCCCOC(=O)\C=C\[C@]1(CO)C\C(=C\CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C23H38O5/c1-6-7-8-9-14-27-21(25)12-13-23(16-24)15-19(22(26)28-23)10-11-20(17(2)3)18(4)5/h10,12-13,17-18,20,24H,6-9,11,14-16H2,1-5H3/b13-12+,19-10-/t23-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
3.5n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085905
PNG
(CHEMBL3085534 | Octanoic acid 2-hydroxymethyl-4-(3...)
Show SMILES CCCCCCCC(=O)OC[C@]1(CO)C\C(=C\CC(C(C)C)C(C)C)C(=O)O1 |r|
Show InChI InChI=1S/C23H40O5/c1-6-7-8-9-10-11-21(25)27-16-23(15-24)14-19(22(26)28-23)12-13-20(17(2)3)18(4)5/h12,17-18,20,24H,6-11,13-16H2,1-5H3/b19-12+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
3.5n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085896
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-hexylidene-2...)
Show SMILES CCCCC\C=C1/CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C21H36O5/c1-6-7-8-9-10-17-12-21(13-22,26-20(17)24)14-25-19(23)11-18(15(2)3)16(4)5/h10,15-16,18,22H,6-9,11-14H2,1-5H3/b17-10+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
5.5n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085887
PNG
(CHEMBL3085533 | Octanoic acid 2-hydroxymethyl-4-(3...)
Show SMILES CCCCCCCC(=O)OC[C@]1(CO)C\C(=C/CC(C(C)C)C(C)C)C(=O)O1 |r|
Show InChI InChI=1S/C23H40O5/c1-6-7-8-9-10-11-21(25)27-16-23(15-24)14-19(22(26)28-23)12-13-20(17(2)3)18(4)5/h12,17-18,20,24H,6-11,13-16H2,1-5H3/b19-12-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
5.90n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085901
PNG
(CHEMBL368346 | Hexanoic acid 2-hydroxymethyl-4-(3-...)
Show SMILES CCCCCC(=O)OCC1(CO)C\C(=C\CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C21H36O5/c1-6-7-8-9-19(23)25-14-21(13-22)12-17(20(24)26-21)10-11-18(15(2)3)16(4)5/h10,15-16,18,22H,6-9,11-14H2,1-5H3/b17-10-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
5.90n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085906
PNG
(CHEMBL171577 | Decanoic acid 2-hydroxymethyl-4-(3-...)
Show SMILES CCCCCCCCCC(=O)OCC1(CO)C\C(=C/CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C25H44O5/c1-6-7-8-9-10-11-12-13-23(27)29-18-25(17-26)16-21(24(28)30-25)14-15-22(19(2)3)20(4)5/h14,19-20,22,26H,6-13,15-18H2,1-5H3/b21-14+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
6.60n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085899
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-hexylidene-2...)
Show SMILES CCCCC\C=C1\CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C21H36O5/c1-6-7-8-9-10-17-12-21(13-22,26-20(17)24)14-25-19(23)11-18(15(2)3)16(4)5/h10,15-16,18,22H,6-9,11-14H2,1-5H3/b17-10-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
7.30n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085891
PNG
(CHEMBL173821 | Hexanoic acid 2-hydroxymethyl-4-(3-...)
Show SMILES [#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#8]-[#6]C1([#6]-[#8])[#6]\[#6](=[#6]/[#6]=[#6](/[#6](-[#6])-[#6])-[#6](-[#6])-[#6])-[#6](=O)-[#8]1
Show InChI InChI=1S/C21H34O5/c1-6-7-8-9-19(23)25-14-21(13-22)12-17(20(24)26-21)10-11-18(15(2)3)16(4)5/h10-11,15-16,22H,6-9,12-14H2,1-5H3/b17-10+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
8.40n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085885
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-decylidene-2...)
Show SMILES CCCCCCCCC\C=C1/CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C25H44O5/c1-6-7-8-9-10-11-12-13-14-21-16-25(17-26,30-24(21)28)18-29-23(27)15-22(19(2)3)20(4)5/h14,19-20,22,26H,6-13,15-18H2,1-5H3/b21-14+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
9.5n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085884
PNG
(3-(2-Hydroxymethyl-4-octadec-9-enylidene-5-oxo-tet...)
Show SMILES CCCCCCCC\C=C/CCCCCCC\C=C1\C[C@](CO)(OC1=O)\C=C\C(=O)OC
Show InChI InChI=1S/C27H44O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-22-27(23-28,32-26(24)30)21-20-25(29)31-2/h10-11,19-21,28H,3-9,12-18,22-23H2,1-2H3/b11-10-,21-20+,24-19-/t27-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
11n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085883
PNG
(CHEMBL367682 | Hexanoic acid 2-hydroxymethyl-4-(3-...)
Show SMILES CCCCCC(=O)OCC1(CO)C\C(=C/CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C21H36O5/c1-6-7-8-9-19(23)25-14-21(13-22)12-17(20(24)26-21)10-11-18(15(2)3)16(4)5/h10,15-16,18,22H,6-9,11-14H2,1-5H3/b17-10+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
11n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085879
PNG
(CHEMBL172715 | Hexanoic acid 2-hydroxymethyl-4-(3-...)
Show SMILES [#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#8]-[#6]C1([#6]-[#8])[#6]\[#6](=[#6]\[#6]=[#6](/[#6](-[#6])-[#6])-[#6](-[#6])-[#6])-[#6](=O)-[#8]1
Show InChI InChI=1S/C21H34O5/c1-6-7-8-9-19(23)25-14-21(13-22)12-17(20(24)26-21)10-11-18(15(2)3)16(4)5/h10-11,15-16,22H,6-9,12-14H2,1-5H3/b17-10-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
12n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091260
PNG
(3-Methyl-butyric acid 4-decylidene-2-hydroxymethyl...)
Show SMILES CCCCCCCCC\C=C1\CC(CO)(COC(=O)CC(C)C)OC1=O
Show InChI InChI=1S/C21H36O5/c1-4-5-6-7-8-9-10-11-12-18-14-21(15-22,26-20(18)24)16-25-19(23)13-17(2)3/h12,17,22H,4-11,13-16H2,1-3H3/b18-12-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
13n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase C alpha


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085878
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-decylidene-2...)
Show SMILES CCCCCCCCC\C=C1\CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C25H44O5/c1-6-7-8-9-10-11-12-13-14-21-16-25(17-26,30-24(21)28)18-29-23(27)15-22(19(2)3)20(4)5/h14,19-20,22,26H,6-13,15-18H2,1-5H3/b21-14-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
13n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase-C alpha (PK-C alpha)


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085878
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-decylidene-2...)
Show SMILES CCCCCCCCC\C=C1\CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C25H44O5/c1-6-7-8-9-10-11-12-13-14-21-16-25(17-26,30-24(21)28)18-29-23(27)15-22(19(2)3)20(4)5/h14,19-20,22,26H,6-13,15-18H2,1-5H3/b21-14-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
13n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085882
PNG
(Butyric acid 2-hydroxymethyl-4-(3-isopropyl-4-meth...)
Show SMILES CCCC(=O)OCC1(CO)C\C(=C\CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C19H32O5/c1-6-7-17(21)23-12-19(11-20)10-15(18(22)24-19)8-9-16(13(2)3)14(4)5/h8,13-14,16,20H,6-7,9-12H2,1-5H3/b15-8-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
19n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085903
PNG
(3-(4-Heptadec-9-enylidene-2-hydroxymethyl-5-oxo-te...)
Show SMILES CCCCCCC\C=C/CCCCCCC\C=C1/C[C@](CO)(OC1=O)\C=C\C(=O)OC
Show InChI InChI=1S/C26H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23-21-26(22-27,31-25(23)29)20-19-24(28)30-2/h9-10,18-20,27H,3-8,11-17,21-22H2,1-2H3/b10-9-,20-19+,23-18+/t26-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
20n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085890
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-butylidene-2...)
Show SMILES CCC\C=C1\CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C19H32O5/c1-6-7-8-15-10-19(11-20,24-18(15)22)12-23-17(21)9-16(13(2)3)14(4)5/h8,13-14,16,20H,6-7,9-12H2,1-5H3/b15-8-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
24n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091246
PNG
(Acetic acid 4-((E)-heptadec-9-enylidene)-2-hydroxy...)
Show SMILES CCCCCCC\C=C\CCCCCCC\C=C1\CC(CO)(COC(C)=O)OC1=O
Show InChI InChI=1S/C25H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23-19-25(20-26,30-24(23)28)21-29-22(2)27/h9-10,18,26H,3-8,11-17,19-21H2,1-2H3/b10-9+,23-18-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
24n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase C alpha


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50049050
PNG
(Acetic acid 2-hydroxymethyl-4-[(Z)-octadec-9-en-(Z...)
Show SMILES CCCCCCCC\C=C/CCCCCCC\C=C1\CC(CO)(COC(C)=O)OC1=O
Show InChI InChI=1S/C26H44O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-20-26(21-27,31-25(24)29)22-30-23(2)28/h10-11,19,27H,3-9,12-18,20-22H2,1-2H3/b11-10-,24-19-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
24n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase-C alpha (PK-C alpha)


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085895
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-butylidene-2...)
Show SMILES CCC\C=C1/CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C19H32O5/c1-6-7-8-15-10-19(11-20,24-18(15)22)12-23-17(21)9-16(13(2)3)14(4)5/h8,13-14,16,20H,6-7,9-12H2,1-5H3/b15-8+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
28n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50087241
PNG
(3-Isopropyl-4-methyl-pentanoic acid (S)-1-hydroxym...)
Show SMILES CC(C)C(CC(=O)OC[C@H](CO)OC(=O)CC(C(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C21H40O5/c1-13(2)18(14(3)4)9-20(23)25-12-17(11-22)26-21(24)10-19(15(5)6)16(7)8/h13-19,22H,9-12H2,1-8H3/t17-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
29n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Displacement of [20-3H] phorbol 12,13-dibutyrate from protein kinase C alpha


Bioorg Med Chem Lett 10: 653-5 (2000)


BindingDB Entry DOI: 10.7270/Q2G16011
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085907
PNG
(3-[2-Hydroxymethyl-4-(3-isopropyl-4-methyl-pentyli...)
Show SMILES CCCCCCOC(=O)\C=C\[C@]1(CO)C\C(=C/CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C23H38O5/c1-6-7-8-9-14-27-21(25)12-13-23(16-24)15-19(22(26)28-23)10-11-20(17(2)3)18(4)5/h10,12-13,17-18,20,24H,6-9,11,14-16H2,1-5H3/b13-12+,19-10+/t23-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
30n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50015677
PNG
((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)
Show SMILES CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC |r|
Show InChI InChI=1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

PubMed
33n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Displacement of [20-3H] phorbol 12,13-dibutyrate from protein kinase C alpha


Bioorg Med Chem Lett 10: 653-5 (2000)


BindingDB Entry DOI: 10.7270/Q2G16011
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50048888
PNG
(Acetic acid 2-hydroxymethyl-5-oxo-4-tetradec-(Z)-y...)
Show SMILES CCCCCCCCCCCCC\C=C1\CC(CO)(COC(C)=O)OC1=O
Show InChI InChI=1S/C22H38O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-20-16-22(17-23,27-21(20)25)18-26-19(2)24/h15,23H,3-14,16-18H2,1-2H3/b20-15-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
35n/an/an/an/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Displacement of [20-3H]-phorbol 12,13-dibutyrate (PDBU) from PKCalpha (C1b domain)


Bioorg Med Chem Lett 8: 3403-8 (1999)


BindingDB Entry DOI: 10.7270/Q2C24VMN
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50087239
PNG
(CHEMBL345343 | Diacylglycerol derivative)
Show SMILES OC[C@@H](COC(=O)C12CC3CC(CC(C3)C1)C2)OC(=O)C12CC3CC(CC(C3)C1)C2 |TLB:23:24:28:21.22.27,14:13:16:8.9.10,14:9:16:15.13.12,27:22:29:28.26.25,27:26:29:21.22.23,THB:23:22:28:29.24.25,12:13:8:16.11.10,12:11:8:15.13.14|
Show InChI InChI=1S/C25H36O5/c26-13-21(30-23(28)25-10-18-4-19(11-25)6-20(5-18)12-25)14-29-22(27)24-7-15-1-16(8-24)3-17(2-15)9-24/h15-21,26H,1-14H2/t15?,16?,17?,18?,19?,20?,21-,24?,25?/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
39n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Displacement of [20-3H] phorbol 12,13-dibutyrate from protein kinase C alpha


Bioorg Med Chem Lett 10: 653-5 (2000)


BindingDB Entry DOI: 10.7270/Q2G16011
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50087237
PNG
(AutoNom Name: | CHEMBL158666)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)O[C@@H](CO)COC(C)=O
Show InChI InChI=1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)28-22(19-24)20-27-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10+/t22-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
50n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Displacement of [20-3H] phorbol 12,13-dibutyrate from protein kinase C alpha


Bioorg Med Chem Lett 10: 653-5 (2000)


BindingDB Entry DOI: 10.7270/Q2G16011
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085893
PNG
(Butyric acid 2-hydroxymethyl-4-(3-isopropyl-4-meth...)
Show SMILES [#6]-[#6]-[#6]-[#6](=O)-[#8]-[#6]C1([#6]-[#8])[#6]\[#6](=[#6]/[#6]=[#6](/[#6](-[#6])-[#6])-[#6](-[#6])-[#6])-[#6](=O)-[#8]1
Show InChI InChI=1S/C19H30O5/c1-6-7-17(21)23-12-19(11-20)10-15(18(22)24-19)8-9-16(13(2)3)14(4)5/h8-9,13-14,20H,6-7,10-12H2,1-5H3/b15-8+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
51n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085898
PNG
(Butyric acid 2-hydroxymethyl-4-(3-isopropyl-4-meth...)
Show SMILES CCCC(=O)OCC1(CO)C\C(=C/CC(C(C)C)C(C)C)C(=O)O1
Show InChI InChI=1S/C19H32O5/c1-6-7-17(21)23-12-19(11-20)10-15(18(22)24-19)8-9-16(13(2)3)14(4)5/h8,13-14,16,20H,6-7,9-12H2,1-5H3/b15-8+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
54n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085894
PNG
(Butyric acid 2-hydroxymethyl-4-(3-isopropyl-4-meth...)
Show SMILES [#6]-[#6]-[#6]-[#6](=O)-[#8]-[#6]C1([#6]-[#8])[#6]\[#6](=[#6]\[#6]=[#6](/[#6](-[#6])-[#6])-[#6](-[#6])-[#6])-[#6](=O)-[#8]1
Show InChI InChI=1S/C19H30O5/c1-6-7-17(21)23-12-19(11-20)10-15(18(22)24-19)8-9-16(13(2)3)14(4)5/h8-9,13-14,20H,6-7,10-12H2,1-5H3/b15-8-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
68n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50048890
PNG
(Acetic acid 2-hydroxymethyl-5-oxo-4-tetradec-(E)-y...)
Show SMILES CCCCCCCCCCCCC\C=C1/CC(CO)(COC(C)=O)OC1=O
Show InChI InChI=1S/C22H38O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-20-16-22(17-23,27-21(20)25)18-26-19(2)24/h15,23H,3-14,16-18H2,1-2H3/b20-15+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
78n/an/an/an/an/an/an/an/a



National Institutes of Health

Curated by ChEMBL


Assay Description
Displacement of [20-3H]-phorbol 12,13-dibutyrate (PDBU) from PKCalpha (C1b domain)


Bioorg Med Chem Lett 8: 3403-8 (1999)


BindingDB Entry DOI: 10.7270/Q2C24VMN
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50087240
PNG
((E)-Octadec-9-enoic acid (S)-1-hydroxymethyl-2-((E...)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC\C=C\CCCCCCCC
Show InChI InChI=1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,37,40H,3-16,21-36H2,1-2H3/b19-17+,20-18+/t37-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
87n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Displacement of [20-3H] phorbol 12,13-dibutyrate from protein kinase C alpha


Bioorg Med Chem Lett 10: 653-5 (2000)


BindingDB Entry DOI: 10.7270/Q2G16011
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50048886
PNG
((Z)-Octadec-9-enoic acid 2-hydroxymethyl-5-oxo-tet...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC1(CO)CCC(=O)O1
Show InChI InChI=1S/C24H42O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)28-21-24(20-25)19-18-23(27)29-24/h9-10,25H,2-8,11-21H2,1H3/b10-9-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
96n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase-C alpha (PK-C alpha)


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091258
PNG
(CHEMBL323750 | Octadec-9-enoic acid 2-hydroxymethy...)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)OCC1(CO)CCC(=O)O1
Show InChI InChI=1S/C24H42O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)28-21-24(20-25)19-18-23(27)29-24/h9-10,25H,2-8,11-21H2,1H3/b10-9+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
96n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase C alpha


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085892
PNG
(Acetic acid 2-hydroxymethyl-4-(3-isopropyl-4-methy...)
Show SMILES CC(C)C(C\C=C1\CC(CO)(COC(C)=O)OC1=O)C(C)C
Show InChI InChI=1S/C17H28O5/c1-11(2)15(12(3)4)7-6-14-8-17(9-18,22-16(14)20)10-21-13(5)19/h6,11-12,15,18H,7-10H2,1-5H3/b14-6-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
123n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085888
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-ethylidene-2...)
Show SMILES C\C=C1/CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C17H28O5/c1-6-13-8-17(9-18,22-16(13)20)10-21-15(19)7-14(11(2)3)12(4)5/h6,11-12,14,18H,7-10H2,1-5H3/b13-6+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
138n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50085900
PNG
(3-Isopropyl-4-methyl-pentanoic acid 4-ethylidene-2...)
Show SMILES C\C=C1\CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O
Show InChI InChI=1S/C17H28O5/c1-6-13-8-17(9-18,22-16(13)20)10-21-15(19)7-14(11(2)3)12(4)5/h6,11-12,14,18H,7-10H2,1-5H3/b13-6-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
164n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Binding Affinity against protein kinase C alpha


J Med Chem 43: 921-44 (2000)


BindingDB Entry DOI: 10.7270/Q2RN372X
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091261
PNG
(3-Isopropyl-4-methyl-pentanoic acid 2-hydroxy-1-[4...)
Show SMILES CC(C)C(C\C=C1\CC(OC1=O)[C@H](CO)OC(=O)CC(C(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C24H42O5/c1-14(2)19(15(3)4)10-9-18-11-21(29-24(18)27)22(13-25)28-23(26)12-20(16(5)6)17(7)8/h9,14-17,19-22,25H,10-13H2,1-8H3/b18-9-/t21?,22-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
327n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase-C alpha (PK-C alpha)


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50091251
PNG
(3-Methyl-butyric acid (S)-2-hydroxy-1-[4-(3-methyl...)
Show SMILES CC(C)C\C=C1\CC(OC1=O)[C@H](CO)OC(=O)CC(C)C
Show InChI InChI=1S/C16H26O5/c1-10(2)5-6-12-8-13(21-16(12)19)14(9-17)20-15(18)7-11(3)4/h6,10-11,13-14,17H,5,7-9H2,1-4H3/b12-6-/t13?,14-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
327n/an/an/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Affinity for protein kinase C alpha


J Med Chem 43: 3209-17 (2000)


BindingDB Entry DOI: 10.7270/Q2WH2P71
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 71 total )  |  Next  |  Last  >>
Jump to: