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Compile Data Set for Download or QSAR

Found 586 hits with Last Name = 'burkhardt' and Initial = 'n'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM123686
PNG
(US8741907, 1)
Show SMILES O=c1[nH]c(CC2CCCCC2)nc2n(ncc12)C1CCCC1
Show InChI InChI=1S/C17H24N4O/c22-17-14-11-18-21(13-8-4-5-9-13)16(14)19-15(20-17)10-12-6-2-1-3-7-12/h11-13H,1-10H2,(H,19,20,22)
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n/an/a 5n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. 2 uL portions of the diluted substa...


US Patent US8741907 (2014)


BindingDB Entry DOI: 10.7270/Q21V5CNH
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM123689
PNG
(US8741907, 6)
Show SMILES O=c1[nH]c(CC2CCC=C2)nc2n(ncc12)C1CCCC1 |c:8|
Show InChI InChI=1S/C16H20N4O/c21-16-13-10-17-20(12-7-3-4-8-12)15(13)18-14(19-16)9-11-5-1-2-6-11/h1,5,10-12H,2-4,6-9H2,(H,18,19,21)
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n/an/a 6n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. 2 uL portions of the diluted substa...


US Patent US8741907 (2014)


BindingDB Entry DOI: 10.7270/Q21V5CNH
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298092
PNG
(3-[3-(2-tert-butoxyethyl)-1,2,4-oxadiazol-5-yl]-2-...)
Show SMILES Cc1nn2c(cc(=O)[nH]c2c1-c1nc(CCOC(C)(C)C)no1)C1CCNCC1
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n/an/a 6n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298254
PNG
(3-(2-methylbutanoyl)-7-(piperidin-4-yl)pyrazolo[1,...)
Show SMILES CCC(C)C(=O)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 8n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298255
PNG
(3-(cyclopropylcarbonyl)-7-(piperidin-4-yl)pyrazolo...)
Show SMILES O=C(C1CC1)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 8n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298041
PNG
(3-(2-methyl-1,3-thiazol-5-yl)-7-(piperidin-4-yl)py...)
Show SMILES Cc1ncc(s1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 8.20n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297950
PNG
(7-(piperidin-4-yl)-3-{5-[4-(trifluoromethyl)phenyl...)
Show SMILES FC(F)(F)c1ccc(cc1)-c1nnc(o1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 8.70n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298115
PNG
(7-(piperidin-4-yl)-3-(piperidin-1-ylcarbonyl)pyraz...)
Show SMILES O=C(N1CCCCC1)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 9n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298123
PNG
(3-(4-cyclohexyl-1,3-thiazol-2-yl)-7-(piperidin-4-y...)
Show SMILES O=c1cc(C2CCNCC2)n2ncc(-c3nc(cs3)C3CCCCC3)c2[nH]1
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n/an/a 9n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298009
PNG
(3-[3-(4-fluorobenzyl)-1,2,4-oxadiazol-5-yl]-7-(pip...)
Show SMILES Fc1ccc(Cc2noc(n2)-c2cnn3c(cc(=O)[nH]c23)C2CCNCC2)cc1
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n/an/a 9.70n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290292
PNG
(2-Oxo-4-(piperidin-4-yl)-1,2-dihydropyrimido[1,2-b...)
Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(C#N)c3c2[nH]1
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n/an/a 10n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298073
PNG
(3-[5-(2-phenylethyl)-1,3,4-oxadiazol-2-yl]-7-(pipe...)
Show SMILES O=c1cc(C2CCNCC2)n2ncc(-c3nnc(CCc4ccccc4)o3)c2[nH]1
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n/an/a 10n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298184
PNG
(Rel-3-{5-[(1R,2S)-2-methylcyclopentyl]-1,2,4-oxadi...)
Show SMILES CC1CCCC1c1nc(no1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 10n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298237
PNG
(3-[3-(2-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-met...)
Show SMILES COc1ccccc1-c1noc(n1)-c1c(C)nn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 10n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298246
PNG
(3-[3-(4-hydroxybenzyl)-1,2,4-oxadiazol-5-yl]-2-met...)
Show SMILES Cc1nn2c(cc(=O)[nH]c2c1-c1nc(Cc2ccc(O)cc2)no1)C1CCNCC1
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n/an/a 10n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290334
PNG
(9-Fluoro-10-phenyl-4-(piperidin-4-yl)pyrimido[1,2-...)
Show SMILES Fc1ccc2nn3c(cc(=O)[nH]c3c2c1-c1ccccc1)C1CCNCC1
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n/an/a 11n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290336
PNG
(10-Chloro-8-methyl-4-(piperidin-4-yl)pyrimido[1,2-...)
Show SMILES Cc1cc(Cl)c2c(c1)nn1c(cc(=O)[nH]c21)C1CCNCC1
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n/an/a 11n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297791
PNG
(Ethyl 5-oxo-7-(piperidin-4-yl)-4,5-dihydropyrazolo...)
Show SMILES CCOC(=O)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297845
PNG
(5-[5-Oxo-7-(piperidin-4-yl)-4,5-dihydropyrazolo[1,...)
Show SMILES O=c1cc(C2CCNCC2)n2ncc(-c3cc(cs3)C#N)c2[nH]1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298063
PNG
(3-[5-(3-chlorobenzyl)-1,3,4-oxadiazol-2-yl]-7-(pip...)
Show SMILES Clc1cccc(Cc2nnc(o2)-c2cnn3c(cc(=O)[nH]c23)C2CCNCC2)c1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298096
PNG
(2-methyl-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-y...)
Show SMILES Cc1nn2c(cc(=O)[nH]c2c1-c1nc(no1)-c1ccc(C)cc1)C1CCNCC1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298098
PNG
(3-(4-ethyl-1,3-thiazol-2-yl)-7-(piperidin-4-yl)pyr...)
Show SMILES CCc1csc(n1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298127
PNG
(3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-2-methyl-7-(...)
Show SMILES Cc1nn2c(cc(=O)[nH]c2c1-c1nnc(o1)C(C)(C)C)C1CCNCC1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298161
PNG
(Cyclobutyl 2-methyl-5-oxo-7-(piperidin-4-yl)-4,5-d...)
Show SMILES Cc1nn2c(cc(=O)[nH]c2c1C(=O)OC1CCC1)C1CCNCC1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298170
PNG
(7-(piperidin-4-yl)-3-(1,2-thiazol-5-yl)pyrazolo[1,...)
Show SMILES O=c1cc(C2CCNCC2)n2ncc(-c3ccns3)c2[nH]1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298253
PNG
(3-(cyclopentylcarbonyl)-7-(piperidin-4-yl)pyrazolo...)
Show SMILES O=C(C1CCCC1)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 11n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297809
PNG
(7-(Piperidin-4-yl)-3-(3-propyl-1,2,4-oxadiazol-5-y...)
Show SMILES CCCc1noc(n1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 12n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297842
PNG
((−)-trans-7-(2-Methylpiperidin-4-yl)-5-oxo-4...)
Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c(cnn12)C#N
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n/an/a 12n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297850
PNG
(3-(Phenylsulfonyl)-7-(piperidin-4-yl)pyrazolo[1,5-...)
Show SMILES O=c1cc(C2CCNCC2)n2ncc(c2[nH]1)S(=O)(=O)c1ccccc1
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n/an/a 12n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298037
PNG
(3-{5-[4-methyl-2-(trifluoromethyl)phenyl]-1,2,4-ox...)
Show SMILES Cc1ccc(-c2nc(no2)-c2cnn3c(cc(=O)[nH]c23)C2CCNCC2)c(c1)C(F)(F)F
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n/an/a 12n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298114
PNG
(3-[(3,3-difluoroazetidin-1-yl)carbonyl]-7-(piperid...)
Show SMILES FC1(F)CN(C1)C(=O)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 12n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298238
PNG
(3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-2-meth...)
Show SMILES Cc1nn2c(cc(=O)[nH]c2c1-c1nc(no1)-c1ccccc1F)C1CCNCC1
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n/an/a 12n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290286
PNG
(7-Bromo-4-(piperidin-4-yl)pyrido[4′,3′...)
Show SMILES Brc1cncc2c1nn1c(cc(=O)[nH]c21)C1CCNCC1
PDB

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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290309
PNG
((−)-trans-10-Ethoxy-4-(2-methylpiperidin-4-y...)
Show SMILES CCOc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNC(C)C1
PDB

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n/an/a 13n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290314
PNG
(10-(2-Fluorophenyl)-4-(piperidin-4-yl)pyrimido[1,2...)
Show SMILES Fc1ccccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1
PDB

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n/an/a 13n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290320
PNG
(10-Cyclopentyl-4-(piperidin-4-yl)pyrimido[1,2-b]in...)
Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(C4CCCC4)c3c2[nH]1
PDB

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n/an/a 13n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290324
PNG
(4-(Piperidin-4-yl)-10-[2-(trifluoromethyl)phenyl]p...)
Show SMILES FC(F)(F)c1ccccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1
PDB

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n/an/a 13n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297797
PNG
(N-Benzyl-5-oxo-7-(piperidin-4-yl)-4,5-dihydropyraz...)
Show SMILES O=C(NCc1ccccc1)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 13n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297808
PNG
(3-(3-Isopropyl-1,2,4-oxadiazol-5-yl)-7-(piperidin-...)
Show SMILES CC(C)c1noc(n1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
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n/an/a 13n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297824
PNG
(4-[5-Oxo-7-(piperidin-4-yl)-4,5-dihydropyrazolo[1,...)
Show SMILES O=c1cc(C2CCNCC2)n2ncc(-c3ccc(cc3)C#N)c2[nH]1
PDB
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n/an/a 13n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297837
PNG
(3-(3-Methoxyphenyl)-7-(piperidin-4-yl)pyrazolo[1,5...)
Show SMILES COc1cccc(c1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
PDB
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n/an/a 13n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM298061
PNG
(3-(5-methyl-4-phenyl-1,3-thiazol-2-yl)-7-(piperidi...)
Show SMILES Cc1sc(nc1-c1ccccc1)-c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
PDB
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n/an/a 13n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290307
PNG
((−)-trans-10-Bromo-4-(2-methylpiperidin-4-yl...)
Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c3c(Br)cccc3nn12
PDB

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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290312
PNG
(4-(Piperidin-4-yl)-10-[4-(trifluoromethyl)phenyl]p...)
Show SMILES FC(F)(F)c1ccc(cc1)-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1
PDB

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n/an/a 14n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290313
PNG
(10-Phenyl-4-(piperidin-4-yl)pyrimido[1,2-b]indazol...)
Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(-c4ccccc4)c3c2[nH]1
PDB

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n/an/a 14n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290269
PNG
(10-Bromo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-...)
Show SMILES Brc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1
PDB

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n/an/a 14n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Plasminogen (aa101-181)


(Homo sapiens (Human))
BDBM290329
PNG
(10-sec-Butyl-4-(piperidin-4-yl)pyrimido[1,2-b]inda...)
Show SMILES CCC(C)c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1
PDB

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n/an/a 14n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10098883 (2018)


Article DOI: 10.1021/jm020455u
BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297796
PNG
(N-Isobutyl-5-oxo-7-(piperidin-4-yl)-4,5-dihydropyr...)
Show SMILES CC(C)CNC(=O)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
PDB
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n/an/a 14n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297798
PNG
(3-(Morpholin-4-ylcarbonyl)-7-(piperidin-4-yl)pyraz...)
Show SMILES O=C(N1CCOCC1)c1cnn2c(cc(=O)[nH]c12)C1CCNCC1
PDB
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n/an/a 14n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM297815
PNG
((−)-trans-3-Chloro-7-(2-methylpiperidin-4-yl...)
Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c(Cl)cnn12
PDB
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent




US Patent US10118930 (2018)


Article DOI: 10.1016/j.bmcl.2005.01.023
BindingDB Entry DOI: 10.7270/Q2QC05J5
More data for this
Ligand-Target Pair
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