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Compile Data Set for Download or QSAR

Found 103 hits with Last Name = 'carmi' and Initial = 'c'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419598
PNG
(CHEMBL1934049)
Show SMILES C[C@H]1CCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C24H32N2/c1-20-6-5-17-26(20)19-22-9-13-24(14-10-22)23-11-7-21(8-12-23)18-25-15-3-2-4-16-25/h7-14,20H,2-6,15-19H2,1H3/t20-/m0/s1
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0.372n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419584
PNG
(CHEMBL1934062)
Show SMILES C[C@H]1CCCN1[C@H](CCCOc1ccccc1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C33H42N2O/c1-27-10-8-24-35(27)33(13-9-25-36-32-11-4-2-5-12-32)31-20-18-30(19-21-31)29-16-14-28(15-17-29)26-34-22-6-3-7-23-34/h2,4-5,11-12,14-21,27,33H,3,6-10,13,22-26H2,1H3/t27-,33+/m0/s1
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0.513n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419598
PNG
(CHEMBL1934049)
Show SMILES C[C@H]1CCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C24H32N2/c1-20-6-5-17-26(20)19-22-9-13-24(14-10-22)23-11-7-21(8-12-23)18-25-15-3-2-4-16-25/h7-14,20H,2-6,15-19H2,1H3/t20-/m0/s1
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0.661n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419595
PNG
(CHEMBL1934061)
Show SMILES COCCC[C@H](N1CCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2O/c1-23-8-6-20-30(23)28(9-7-21-31-2)27-16-14-26(15-17-27)25-12-10-24(11-13-25)22-29-18-4-3-5-19-29/h10-17,23,28H,3-9,18-22H2,1-2H3/t23-,28-/m0/s1
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0.871n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419588
PNG
(CHEMBL1934057)
Show SMILES CCCC[C@H](N1CCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2/c1-3-4-10-28(30-21-8-9-23(30)2)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-29-19-6-5-7-20-29/h11-18,23,28H,3-10,19-22H2,1-2H3/t23-,28-/m0/s1
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1.26n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419582
PNG
(CHEMBL1934064)
Show SMILES COc1ccc(OCCC[C@@H](N2CCC[C@@H]2C)c2ccc(cc2)-c2ccc(CN3CCCCC3)cc2)cc1 |r|
Show InChI InChI=1S/C34H44N2O2/c1-27-8-6-24-36(27)34(9-7-25-38-33-20-18-32(37-2)19-21-33)31-16-14-30(15-17-31)29-12-10-28(11-13-29)26-35-22-4-3-5-23-35/h10-21,27,34H,3-9,22-26H2,1-2H3/t27-,34+/m0/s1
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1.26n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419597
PNG
(CHEMBL1934053)
Show SMILES CCCCC(N1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C28H40N2/c1-2-3-10-28(30-21-8-5-9-22-30)27-17-15-26(16-18-27)25-13-11-24(12-14-25)23-29-19-6-4-7-20-29/h11-18,28H,2-10,19-23H2,1H3
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1.29n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419588
PNG
(CHEMBL1934057)
Show SMILES CCCC[C@H](N1CCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2/c1-3-4-10-28(30-21-8-9-23(30)2)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-29-19-6-5-7-20-29/h11-18,23,28H,3-10,19-22H2,1-2H3/t23-,28-/m0/s1
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1.41n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419593
PNG
(CHEMBL1934048)
Show SMILES C[C@@H]1CCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C24H32N2/c1-20-6-5-17-26(20)19-22-9-13-24(14-10-22)23-11-7-21(8-12-23)18-25-15-3-2-4-16-25/h7-14,20H,2-6,15-19H2,1H3/t20-/m1/s1
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1.48n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419585
PNG
(CHEMBL1934060)
Show SMILES COCCC[C@@H](N1CCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2O/c1-23-8-6-20-30(23)28(9-7-21-31-2)27-16-14-26(15-17-27)25-12-10-24(11-13-25)22-29-18-4-3-5-19-29/h10-17,23,28H,3-9,18-22H2,1-2H3/t23-,28+/m0/s1
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1.48n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419596
PNG
(CHEMBL1934056)
Show SMILES CCCC[C@@H](N1CCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2/c1-3-4-10-28(30-21-8-9-23(30)2)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-29-19-6-5-7-20-29/h11-18,23,28H,3-10,19-22H2,1-2H3/t23-,28+/m0/s1
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1.55n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419595
PNG
(CHEMBL1934061)
Show SMILES COCCC[C@H](N1CCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2O/c1-23-8-6-20-30(23)28(9-7-21-31-2)27-16-14-26(15-17-27)25-12-10-24(11-13-25)22-29-18-4-3-5-19-29/h10-17,23,28H,3-9,18-22H2,1-2H3/t23-,28-/m0/s1
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1.78n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419585
PNG
(CHEMBL1934060)
Show SMILES COCCC[C@@H](N1CCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2O/c1-23-8-6-20-30(23)28(9-7-21-31-2)27-16-14-26(15-17-27)25-12-10-24(11-13-25)22-29-18-4-3-5-19-29/h10-17,23,28H,3-9,18-22H2,1-2H3/t23-,28+/m0/s1
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2n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419581
PNG
(CHEMBL1934065)
Show SMILES COc1ccc(OCCC[C@H](N2CCC[C@@H]2C)c2ccc(cc2)-c2ccc(CN3CCCCC3)cc2)cc1 |r|
Show InChI InChI=1S/C34H44N2O2/c1-27-8-6-24-36(27)34(9-7-25-38-33-20-18-32(37-2)19-21-33)31-16-14-30(15-17-31)29-12-10-28(11-13-29)26-35-22-4-3-5-23-35/h10-21,27,34H,3-9,22-26H2,1-2H3/t27-,34-/m0/s1
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2.04n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419581
PNG
(CHEMBL1934065)
Show SMILES COc1ccc(OCCC[C@H](N2CCC[C@@H]2C)c2ccc(cc2)-c2ccc(CN3CCCCC3)cc2)cc1 |r|
Show InChI InChI=1S/C34H44N2O2/c1-27-8-6-24-36(27)34(9-7-25-38-33-20-18-32(37-2)19-21-33)31-16-14-30(15-17-31)29-12-10-28(11-13-29)26-35-22-4-3-5-23-35/h10-21,27,34H,3-9,22-26H2,1-2H3/t27-,34-/m0/s1
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2.09n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419579
PNG
(CHEMBL1934054)
Show SMILES CCCC[C@H](N1CCC[C@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2/c1-3-4-10-28(30-21-8-9-23(30)2)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-29-19-6-5-7-20-29/h11-18,23,28H,3-10,19-22H2,1-2H3/t23-,28+/m1/s1
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2.34n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419589
PNG
(CHEMBL1934055)
Show SMILES CCCC[C@@H](N1CCC[C@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2/c1-3-4-10-28(30-21-8-9-23(30)2)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-29-19-6-5-7-20-29/h11-18,23,28H,3-10,19-22H2,1-2H3/t23-,28-/m1/s1
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2.45n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419586
PNG
(CHEMBL1934059)
Show SMILES CCCC[C@H](N1CCCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C29H42N2/c1-3-4-11-29(31-22-9-6-10-24(31)2)28-18-16-27(17-19-28)26-14-12-25(13-15-26)23-30-20-7-5-8-21-30/h12-19,24,29H,3-11,20-23H2,1-2H3/t24-,29-/m0/s1
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2.45n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419583
PNG
(CHEMBL1934063)
Show SMILES C[C@H]1CCCN1[C@@H](CCCOc1ccccc1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C33H42N2O/c1-27-10-8-24-35(27)33(13-9-25-36-32-11-4-2-5-12-32)31-20-18-30(19-21-31)29-16-14-28(15-17-29)26-34-22-6-3-7-23-34/h2,4-5,11-12,14-21,27,33H,3,6-10,13,22-26H2,1H3/t27-,33-/m0/s1
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2.57n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419587
PNG
(CHEMBL1934058)
Show SMILES CCCC[C@@H](N1CCCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C29H42N2/c1-3-4-11-29(31-22-9-6-10-24(31)2)28-18-16-27(17-19-28)26-14-12-25(13-15-26)23-30-20-7-5-8-21-30/h12-19,24,29H,3-11,20-23H2,1-2H3/t24-,29+/m0/s1
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3.02n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419593
PNG
(CHEMBL1934048)
Show SMILES C[C@@H]1CCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C24H32N2/c1-20-6-5-17-26(20)19-22-9-13-24(14-10-22)23-11-7-21(8-12-23)18-25-15-3-2-4-16-25/h7-14,20H,2-6,15-19H2,1H3/t20-/m1/s1
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3.55n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419597
PNG
(CHEMBL1934053)
Show SMILES CCCCC(N1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C28H40N2/c1-2-3-10-28(30-21-8-5-9-22-30)27-17-15-26(16-18-27)25-13-11-24(12-14-25)23-29-19-6-4-7-20-29/h11-18,28H,2-10,19-23H2,1H3
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4.27n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419583
PNG
(CHEMBL1934063)
Show SMILES C[C@H]1CCCN1[C@@H](CCCOc1ccccc1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C33H42N2O/c1-27-10-8-24-35(27)33(13-9-25-36-32-11-4-2-5-12-32)31-20-18-30(19-21-31)29-16-14-28(15-17-29)26-34-22-6-3-7-23-34/h2,4-5,11-12,14-21,27,33H,3,6-10,13,22-26H2,1H3/t27-,33-/m0/s1
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4.68n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419590
PNG
(CHEMBL1934052)
Show SMILES C[C@@H]1CCCN1Cc1ccc(cc1)-c1ccc(cc1)C(Cc1ccccc1)N1CCCCC1 |r|
Show InChI InChI=1S/C31H38N2/c1-25-9-8-22-33(25)24-27-12-14-28(15-13-27)29-16-18-30(19-17-29)31(32-20-6-3-7-21-32)23-26-10-4-2-5-11-26/h2,4-5,10-19,25,31H,3,6-9,20-24H2,1H3/t25-,31?/m1/s1
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5.62n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419582
PNG
(CHEMBL1934064)
Show SMILES COc1ccc(OCCC[C@@H](N2CCC[C@@H]2C)c2ccc(cc2)-c2ccc(CN3CCCCC3)cc2)cc1 |r|
Show InChI InChI=1S/C34H44N2O2/c1-27-8-6-24-36(27)34(9-7-25-38-33-20-18-32(37-2)19-21-33)31-16-14-30(15-17-31)29-12-10-28(11-13-29)26-35-22-4-3-5-23-35/h10-21,27,34H,3-9,22-26H2,1-2H3/t27-,34+/m0/s1
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6.61n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419584
PNG
(CHEMBL1934062)
Show SMILES C[C@H]1CCCN1[C@H](CCCOc1ccccc1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C33H42N2O/c1-27-10-8-24-35(27)33(13-9-25-36-32-11-4-2-5-12-32)31-20-18-30(19-21-31)29-16-14-28(15-17-29)26-34-22-6-3-7-23-34/h2,4-5,11-12,14-21,27,33H,3,6-10,13,22-26H2,1H3/t27-,33+/m0/s1
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6.61n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419596
PNG
(CHEMBL1934056)
Show SMILES CCCC[C@@H](N1CCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2/c1-3-4-10-28(30-21-8-9-23(30)2)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-29-19-6-5-7-20-29/h11-18,23,28H,3-10,19-22H2,1-2H3/t23-,28+/m0/s1
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8.71n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419589
PNG
(CHEMBL1934055)
Show SMILES CCCC[C@@H](N1CCC[C@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2/c1-3-4-10-28(30-21-8-9-23(30)2)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-29-19-6-5-7-20-29/h11-18,23,28H,3-10,19-22H2,1-2H3/t23-,28-/m1/s1
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12.6n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419579
PNG
(CHEMBL1934054)
Show SMILES CCCC[C@H](N1CCC[C@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C28H40N2/c1-3-4-10-28(30-21-8-9-23(30)2)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-29-19-6-5-7-20-29/h11-18,23,28H,3-10,19-22H2,1-2H3/t23-,28+/m1/s1
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16.2n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419591
PNG
(CHEMBL1934051)
Show SMILES CN(C)C(Cc1ccccc1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C28H34N2/c1-29(2)28(21-23-9-5-3-6-10-23)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-30-19-7-4-8-20-30/h3,5-6,9-18,28H,4,7-8,19-22H2,1-2H3
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16.6n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419592
PNG
(CHEMBL1934050)
Show SMILES C(C(N1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1)c1ccccc1
Show InChI InChI=1S/C31H38N2/c1-4-10-26(11-5-1)24-31(33-22-8-3-9-23-33)30-18-16-29(17-19-30)28-14-12-27(13-15-28)25-32-20-6-2-7-21-32/h1,4-5,10-19,31H,2-3,6-9,20-25H2
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19.1n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419586
PNG
(CHEMBL1934059)
Show SMILES CCCC[C@H](N1CCCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C29H42N2/c1-3-4-11-29(31-22-9-6-10-24(31)2)28-18-16-27(17-19-28)26-14-12-25(13-15-26)23-30-20-7-5-8-21-30/h12-19,24,29H,3-11,20-23H2,1-2H3/t24-,29-/m0/s1
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26.3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419587
PNG
(CHEMBL1934058)
Show SMILES CCCC[C@@H](N1CCCC[C@@H]1C)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 |r|
Show InChI InChI=1S/C29H42N2/c1-3-4-11-29(31-22-9-6-10-24(31)2)28-18-16-27(17-19-28)26-14-12-25(13-15-26)23-30-20-7-5-8-21-30/h12-19,24,29H,3-11,20-23H2,1-2H3/t24-,29+/m0/s1
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26.3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419590
PNG
(CHEMBL1934052)
Show SMILES C[C@@H]1CCCN1Cc1ccc(cc1)-c1ccc(cc1)C(Cc1ccccc1)N1CCCCC1 |r|
Show InChI InChI=1S/C31H38N2/c1-25-9-8-22-33(25)24-27-12-14-28(15-13-27)29-16-18-30(19-17-29)31(32-20-6-3-7-21-32)23-26-10-4-2-5-11-26/h2,4-5,10-19,25,31H,3,6-9,20-24H2,1H3/t25-,31?/m1/s1
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29.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419591
PNG
(CHEMBL1934051)
Show SMILES CN(C)C(Cc1ccccc1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C28H34N2/c1-29(2)28(21-23-9-5-3-6-10-23)27-17-15-26(16-18-27)25-13-11-24(12-14-25)22-30-19-7-4-8-20-30/h3,5-6,9-18,28H,4,7-8,19-22H2,1-2H3
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30.2n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419592
PNG
(CHEMBL1934050)
Show SMILES C(C(N1CCCCC1)c1ccc(cc1)-c1ccc(CN2CCCCC2)cc1)c1ccccc1
Show InChI InChI=1S/C31H38N2/c1-4-10-26(11-5-1)24-31(33-22-8-3-9-23-33)30-18-16-29(17-19-30)28-14-12-27(13-15-28)25-32-20-6-2-7-21-32/h1,4-5,10-19,31H,2-3,6-9,20-25H2
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112n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419594
PNG
(CHEMBL1934066)
Show SMILES CCCCCc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C23H31N/c1-2-3-5-8-20-9-13-22(14-10-20)23-15-11-21(12-16-23)19-24-17-6-4-7-18-24/h9-16H,2-8,17-19H2,1H3
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1.29E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50419580
PNG
(CHEMBL1934067)
Show SMILES CCCCC(N1CCCCC1)c1ccc(cc1)-c1ccc(C)cc1
Show InChI InChI=1S/C23H31N/c1-3-4-8-23(24-17-6-5-7-18-24)22-15-13-21(14-16-22)20-11-9-19(2)10-12-20/h9-16,23H,3-8,17-18H2,1-2H3
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1.35E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from human histamine H3 receptor expressed in GPCR97 transfected human SK-N-MC cells


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419580
PNG
(CHEMBL1934067)
Show SMILES CCCCC(N1CCCCC1)c1ccc(cc1)-c1ccc(C)cc1
Show InChI InChI=1S/C23H31N/c1-3-4-8-23(24-17-6-5-7-18-24)22-15-13-21(14-16-22)20-11-9-19(2)10-12-20/h9-16,23H,3-8,17-18H2,1-2H3
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4.37E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50419594
PNG
(CHEMBL1934066)
Show SMILES CCCCCc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C23H31N/c1-2-3-5-8-20-9-13-22(14-10-20)23-15-11-21(12-16-23)19-24-17-6-4-7-18-24/h9-16H,2-8,17-19H2,1H3
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6.03E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]RAMHA from rat histamine H3 receptor in rat cerebral cortex membranes


Eur J Med Chem 48: 214-30 (2012)


Article DOI: 10.1016/j.ejmech.2011.12.019
BindingDB Entry DOI: 10.7270/Q23X87XW
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50307941
PNG
(CHEMBL592617 | N-(4-(3-Bromoanilino)quinazolin-6-y...)
Show SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)CC#N)cc23)c1
Show InChI InChI=1S/C17H12BrN5O/c18-11-2-1-3-12(8-11)23-17-14-9-13(22-16(24)6-7-19)4-5-15(14)20-10-21-17/h1-5,8-10H,6H2,(H,22,24)(H,20,21,23)
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n/an/a 0.170n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorometry


J Med Chem 53: 2038-50 (2010)


Article DOI: 10.1021/jm901558p
BindingDB Entry DOI: 10.7270/Q2736R1N
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50383051
PNG
(CHEMBL2031302)
Show SMILES CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C
Show InChI InChI=1S/C19H16ClFN4O2/c1-3-18(26)25-16-8-12-15(9-17(16)27-4-2)22-10-23-19(12)24-11-5-6-14(21)13(20)7-11/h3,5-10H,1,4H2,2H3,(H,25,26)(H,22,23,24)
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n/an/a 0.180n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis


J Med Chem 55: 2251-64 (2012)


Article DOI: 10.1021/jm201507x
BindingDB Entry DOI: 10.7270/Q20K29M1
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50383049
PNG
(CHEMBL2031300)
Show SMILES CN1CCN(CCC(=O)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)CC1
Show InChI InChI=1S/C22H25BrN6O/c1-28-9-11-29(12-10-28)8-7-21(30)26-18-5-6-20-19(14-18)22(25-15-24-20)27-17-4-2-3-16(23)13-17/h2-6,13-15H,7-12H2,1H3,(H,26,30)(H,24,25,27)
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n/an/a 0.230n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis


J Med Chem 55: 2251-64 (2012)


Article DOI: 10.1021/jm201507x
BindingDB Entry DOI: 10.7270/Q20K29M1
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50383047
PNG
(CHEMBL2031298)
Show SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)CCN4CCCCC4)cc23)c1
Show InChI InChI=1S/C22H24BrN5O/c23-16-5-4-6-17(13-16)27-22-19-14-18(7-8-20(19)24-15-25-22)26-21(29)9-12-28-10-2-1-3-11-28/h4-8,13-15H,1-3,9-12H2,(H,26,29)(H,24,25,27)
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n/an/a 0.270n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis


J Med Chem 55: 2251-64 (2012)


Article DOI: 10.1021/jm201507x
BindingDB Entry DOI: 10.7270/Q20K29M1
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50383052
PNG
(CHEMBL2031303)
Show SMILES CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CCN(C)C
Show InChI InChI=1S/C21H23ClFN5O2/c1-4-30-19-11-17-14(10-18(19)27-20(29)7-8-28(2)3)21(25-12-24-17)26-13-5-6-16(23)15(22)9-13/h5-6,9-12H,4,7-8H2,1-3H3,(H,27,29)(H,24,25,26)
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n/an/a 0.270n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis


J Med Chem 55: 2251-64 (2012)


Article DOI: 10.1021/jm201507x
BindingDB Entry DOI: 10.7270/Q20K29M1
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50383046
PNG
(CHEMBL2031297)
Show SMILES CN(C)CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
Show InChI InChI=1S/C19H20BrN5O/c1-25(2)9-8-18(26)23-15-6-7-17-16(11-15)19(22-12-21-17)24-14-5-3-4-13(20)10-14/h3-7,10-12H,8-9H2,1-2H3,(H,23,26)(H,21,22,24)
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n/an/a 0.280n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis


J Med Chem 55: 2251-64 (2012)


Article DOI: 10.1021/jm201507x
BindingDB Entry DOI: 10.7270/Q20K29M1
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50383054
PNG
(CHEMBL2031305)
Show SMILES CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CCN1CCOCC1
Show InChI InChI=1S/C23H25ClFN5O3/c1-2-33-21-13-19-16(12-20(21)29-22(31)5-6-30-7-9-32-10-8-30)23(27-14-26-19)28-15-3-4-18(25)17(24)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,29,31)(H,26,27,28)
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n/an/a 0.290n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis


J Med Chem 55: 2251-64 (2012)


Article DOI: 10.1021/jm201507x
BindingDB Entry DOI: 10.7270/Q20K29M1
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50419129
PNG
(CHEMBL1830441)
Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCCCCc2ccccc2)c1
Show InChI InChI=1S/C24H24N2O3/c25-23(27)21-13-6-11-19(16-21)20-12-7-14-22(17-20)29-24(28)26-15-5-4-10-18-8-2-1-3-9-18/h1-3,6-9,11-14,16-17H,4-5,10,15H2,(H2,25,27)(H,26,28)
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n/an/a 0.331n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Displacement of [3H]-anandamide from rat brain FAAH after 30 mins by scintillation counting


Eur J Med Chem 46: 4466-73 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.021
BindingDB Entry DOI: 10.7270/Q2FB546B
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50307940
PNG
(CHEMBL603266 | N-(4-(3-Bromoanilino)quinazolin-6-y...)
Show SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)Cn4sccc4=O)cc23)c1
Show InChI InChI=1S/C19H14BrN5O2S/c20-12-2-1-3-13(8-12)24-19-15-9-14(4-5-16(15)21-11-22-19)23-17(26)10-25-18(27)6-7-28-25/h1-9,11H,10H2,(H,23,26)(H,21,22,24)
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n/an/a 0.360n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorometry


J Med Chem 53: 2038-50 (2010)


Article DOI: 10.1021/jm901558p
BindingDB Entry DOI: 10.7270/Q2736R1N
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50307939
PNG
(CHEMBL599863 | N-[2-[(4-(3-Bromoanilino)quinazolin...)
Show SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)CNC(=O)Oc4ccccc4)cc23)c1
Show InChI InChI=1S/C23H18BrN5O3/c24-15-5-4-6-16(11-15)29-22-19-12-17(9-10-20(19)26-14-27-22)28-21(30)13-25-23(31)32-18-7-2-1-3-8-18/h1-12,14H,13H2,(H,25,31)(H,28,30)(H,26,27,29)
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n/an/a 0.370n/an/an/an/an/an/a



Universit£ degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorometry


J Med Chem 53: 2038-50 (2010)


Article DOI: 10.1021/jm901558p
BindingDB Entry DOI: 10.7270/Q2736R1N
More data for this
Ligand-Target Pair
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