new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 720 hits with Last Name = 'cow' and Initial = 'c'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50002595
PNG
(SOLABEGRON | Solabegron)
Show SMILES O[C@@H](CNCCNc1cccc(c1)-c1cccc(c1)C(O)=O)c1cccc(Cl)c1
Show InChI InChI=1S/C23H23ClN2O3/c24-20-8-2-6-18(13-20)22(27)15-25-10-11-26-21-9-3-5-17(14-21)16-4-1-7-19(12-16)23(28)29/h1-9,12-14,22,25-27H,10-11,15H2,(H,28,29)/t22-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
398n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [125I]cyanopindolol from human cloned beta-1 adrenergic receptor expressed in Sf9 cells


J Med Chem 49: 2758-71 (2006)

Checked by Author
Article DOI: 10.1021/jm0509445
BindingDB Entry DOI: 10.7270/Q2KD20D5
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50002595
PNG
(SOLABEGRON | Solabegron)
Show SMILES O[C@@H](CNCCNc1cccc(c1)-c1cccc(c1)C(O)=O)c1cccc(Cl)c1
Show InChI InChI=1S/C23H23ClN2O3/c24-20-8-2-6-18(13-20)22(27)15-25-10-11-26-21-9-3-5-17(14-21)16-4-1-7-19(12-16)23(28)29/h1-9,12-14,22,25-27H,10-11,15H2,(H,28,29)/t22-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
1.59E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [125I]cyanopindolol from human cloned beta-2 adrenergic receptor expressed in Sf9 cells


J Med Chem 49: 2758-71 (2006)

Checked by Author
Article DOI: 10.1021/jm0509445
BindingDB Entry DOI: 10.7270/Q2KD20D5
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50422411
PNG
(CHEMBL154419)
Show SMILES C[C@H](CNc1ccc(CC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C19H23ClN2O3/c1-13(21-12-18(23)15-3-2-4-16(20)10-15)11-22-17-7-5-14(6-8-17)9-19(24)25/h2-8,10,13,18,21-23H,9,11-12H2,1H3,(H,24,25)/t13-,18+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 794n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...


J Med Chem 45: 567-83 (2002)


BindingDB Entry DOI: 10.7270/Q2W0976P
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50422411
PNG
(CHEMBL154419)
Show SMILES C[C@H](CNc1ccc(CC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C19H23ClN2O3/c1-13(21-12-18(23)15-3-2-4-16(20)10-15)11-22-17-7-5-14(6-8-17)9-19(24)25/h2-8,10,13,18,21-23H,9,11-12H2,1H3,(H,24,25)/t13-,18+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...


J Med Chem 45: 567-83 (2002)


BindingDB Entry DOI: 10.7270/Q2W0976P
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50422410
PNG
(CHEMBL348501)
Show SMILES C[C@H](CNc1ccc(CC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C26H30ClN3O4S/c1-18-6-12-24(13-7-18)35(33,34)30-26(32)14-20-8-10-23(11-9-20)29-16-19(2)28-17-25(31)21-4-3-5-22(27)15-21/h3-13,15,19,25,28-29,31H,14,16-17H2,1-2H3,(H,30,32)/t19-,25+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...


J Med Chem 45: 567-83 (2002)


BindingDB Entry DOI: 10.7270/Q2W0976P
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50422409
PNG
(CHEMBL347582)
Show SMILES C[C@H](CNc1cccc(CC(=O)NS(=O)(=O)c2ccc(C)cc2)c1)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C26H30ClN3O4S/c1-18-9-11-24(12-10-18)35(33,34)30-26(32)14-20-5-3-8-23(13-20)29-16-19(2)28-17-25(31)21-6-4-7-22(27)15-21/h3-13,15,19,25,28-29,31H,14,16-17H2,1-2H3,(H,30,32)/t19-,25+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Receptor binding assay(Beta-1 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...


J Med Chem 45: 567-83 (2002)


BindingDB Entry DOI: 10.7270/Q2W0976P
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50422410
PNG
(CHEMBL348501)
Show SMILES C[C@H](CNc1ccc(CC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C26H30ClN3O4S/c1-18-6-12-24(13-7-18)35(33,34)30-26(32)14-20-8-10-23(11-9-20)29-16-19(2)28-17-25(31)21-4-3-5-22(27)15-21/h3-13,15,19,25,28-29,31H,14,16-17H2,1-2H3,(H,30,32)/t19-,25+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...


J Med Chem 45: 567-83 (2002)


BindingDB Entry DOI: 10.7270/Q2W0976P
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50422409
PNG
(CHEMBL347582)
Show SMILES C[C@H](CNc1cccc(CC(=O)NS(=O)(=O)c2ccc(C)cc2)c1)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C26H30ClN3O4S/c1-18-9-11-24(12-10-18)35(33,34)30-26(32)14-20-5-3-8-23(13-20)29-16-19(2)28-17-25(31)21-6-4-7-22(27)15-21/h3-13,15,19,25,28-29,31H,14,16-17H2,1-2H3,(H,30,32)/t19-,25+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.58E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Receptor binding assay(Beta-2 adrenergic receptor) carried out with membranes prepared from human recombinant Sf9 cells expressing the cloned human r...


J Med Chem 45: 567-83 (2002)


BindingDB Entry DOI: 10.7270/Q2W0976P
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28764
PNG
(2-[3-chloro-4-(4-{[2-(2,4-dichlorophenoxy)ethyl]ca...)
Show SMILES OC(=O)Cc1ccc(-c2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C26H19Cl3N2O5/c27-17-7-9-21(20(29)14-17)35-11-10-30-26(34)23-24(31-36-25(23)16-4-2-1-3-5-16)18-8-6-15(12-19(18)28)13-22(32)33/h1-9,12,14H,10-11,13H2,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 80n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28765
PNG
(2-{3-chloro-4-[(4-{[2-(2,4-dichlorophenoxy)ethyl]c...)
Show SMILES OC(=O)Cc1ccc(OCc2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C27H21Cl3N2O6/c28-18-7-9-22(20(30)14-18)36-11-10-31-27(35)25-21(32-38-26(25)17-4-2-1-3-5-17)15-37-23-8-6-16(12-19(23)29)13-24(33)34/h1-9,12,14H,10-11,13,15H2,(H,31,35)(H,33,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28766
PNG
(2-[4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1ccc(cc1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-10-11-21(20(28)15-19)34-13-12-29-26(33)23-24(17-8-6-16(7-9-17)14-22(31)32)30-35-25(23)18-4-2-1-3-5-18/h1-11,15H,12-14H2,(H,29,33)(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 720n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28767
PNG
(4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-5-p...)
Show SMILES OC(=O)c1ccc(cc1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C25H18Cl2N2O5/c26-18-10-11-20(19(27)14-18)33-13-12-28-24(30)21-22(15-6-8-17(9-7-15)25(31)32)29-34-23(21)16-4-2-1-3-5-16/h1-11,14H,12-13H2,(H,28,30)(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28768
PNG
(2-[4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES Cc1cc(ccc1OCC(O)=O)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O6/c1-16-13-18(7-9-21(16)36-15-23(32)33)25-24(26(37-31-25)17-5-3-2-4-6-17)27(34)30-11-12-35-22-10-8-19(28)14-20(22)29/h2-10,13-14H,11-12,15H2,1H3,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 200n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28769
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-9-10-21(20(28)15-19)34-12-11-29-26(33)23-24(18-8-4-5-16(13-18)14-22(31)32)30-35-25(23)17-6-2-1-3-7-17/h1-10,13,15H,11-12,14H2,(H,29,33)(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/an/an/a 70n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28770
PNG
(3-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)CCc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O5/c28-20-10-11-22(21(29)16-20)35-14-13-30-27(34)24-25(31-36-26(24)18-6-2-1-3-7-18)19-8-4-5-17(15-19)9-12-23(32)33/h1-8,10-11,15-16H,9,12-14H2,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 970n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28771
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES COc1ccc(CC(O)=O)cc1-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O6/c1-35-21-9-7-16(14-23(32)33)13-19(21)25-24(26(37-31-25)17-5-3-2-4-6-17)27(34)30-11-12-36-22-10-8-18(28)15-20(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 560n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28772
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES CC(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1
Show InChI InChI=1S/C23H22Cl2N2O5/c1-13(2)22-20(21(27-32-22)15-5-3-4-14(10-15)11-19(28)29)23(30)26-8-9-31-18-7-6-16(24)12-17(18)25/h3-7,10,12-13H,8-9,11H2,1-2H3,(H,26,30)(H,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 1.07E+3n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28773
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(-c2ccco2)c1C(=O)NCCOc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H18Cl2N2O6/c25-16-6-7-18(17(26)13-16)33-10-8-27-24(31)21-22(28-34-23(21)19-5-2-9-32-19)15-4-1-3-14(11-15)12-20(29)30/h1-7,9,11,13H,8,10,12H2,(H,27,31)(H,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 90n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28774
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES Cc1ccccc1-c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1
Show InChI InChI=1S/C27H22Cl2N2O5/c1-16-5-2-3-8-20(16)26-24(25(31-36-26)18-7-4-6-17(13-18)14-23(32)33)27(34)30-11-12-35-22-10-9-19(28)15-21(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 50n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28775
PNG
(2-{3-[5-(2-chlorophenyl)-4-{[2-(2,4-dichlorophenox...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1Cl
Show InChI InChI=1S/C26H19Cl3N2O5/c27-17-8-9-21(20(29)14-17)35-11-10-30-26(34)23-24(16-5-3-4-15(12-16)13-22(32)33)31-36-25(23)18-6-1-2-7-19(18)28/h1-9,12,14H,10-11,13H2,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 60n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28764
PNG
(2-[3-chloro-4-(4-{[2-(2,4-dichlorophenoxy)ethyl]ca...)
Show SMILES OC(=O)Cc1ccc(-c2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C26H19Cl3N2O5/c27-17-7-9-21(20(29)14-17)35-11-10-30-26(34)23-24(31-36-25(23)16-4-2-1-3-5-16)18-8-6-15(12-19(18)28)13-22(32)33/h1-9,12,14H,10-11,13H2,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28765
PNG
(2-{3-chloro-4-[(4-{[2-(2,4-dichlorophenoxy)ethyl]c...)
Show SMILES OC(=O)Cc1ccc(OCc2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C27H21Cl3N2O6/c28-18-7-9-22(20(30)14-18)36-11-10-31-27(35)25-21(32-38-26(25)17-4-2-1-3-5-17)15-37-23-8-6-16(12-19(23)29)13-24(33)34/h1-9,12,14H,10-11,13,15H2,(H,31,35)(H,33,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28766
PNG
(2-[4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1ccc(cc1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-10-11-21(20(28)15-19)34-13-12-29-26(33)23-24(17-8-6-16(7-9-17)14-22(31)32)30-35-25(23)18-4-2-1-3-5-18/h1-11,15H,12-14H2,(H,29,33)(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28767
PNG
(4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-5-p...)
Show SMILES OC(=O)c1ccc(cc1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C25H18Cl2N2O5/c26-18-10-11-20(19(27)14-18)33-13-12-28-24(30)21-22(15-6-8-17(9-7-15)25(31)32)29-34-23(21)16-4-2-1-3-5-16/h1-11,14H,12-13H2,(H,28,30)(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28768
PNG
(2-[4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES Cc1cc(ccc1OCC(O)=O)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O6/c1-16-13-18(7-9-21(16)36-15-23(32)33)25-24(26(37-31-25)17-5-3-2-4-6-17)27(34)30-11-12-35-22-10-8-19(28)14-20(22)29/h2-10,13-14H,11-12,15H2,1H3,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28769
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-9-10-21(20(28)15-19)34-12-11-29-26(33)23-24(18-8-4-5-16(13-18)14-22(31)32)30-35-25(23)17-6-2-1-3-7-17/h1-10,13,15H,11-12,14H2,(H,29,33)(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28770
PNG
(3-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)CCc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O5/c28-20-10-11-22(21(29)16-20)35-14-13-30-27(34)24-25(31-36-26(24)18-6-2-1-3-7-18)19-8-4-5-17(15-19)9-12-23(32)33/h1-8,10-11,15-16H,9,12-14H2,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28771
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES COc1ccc(CC(O)=O)cc1-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O6/c1-35-21-9-7-16(14-23(32)33)13-19(21)25-24(26(37-31-25)17-5-3-2-4-6-17)27(34)30-11-12-36-22-10-8-18(28)15-20(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28772
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES CC(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1
Show InChI InChI=1S/C23H22Cl2N2O5/c1-13(2)22-20(21(27-32-22)15-5-3-4-14(10-15)11-19(28)29)23(30)26-8-9-31-18-7-6-16(24)12-17(18)25/h3-7,10,12-13H,8-9,11H2,1-2H3,(H,26,30)(H,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28773
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(-c2ccco2)c1C(=O)NCCOc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H18Cl2N2O6/c25-16-6-7-18(17(26)13-16)33-10-8-27-24(31)21-22(28-34-23(21)19-5-2-9-32-19)15-4-1-3-14(11-15)12-20(29)30/h1-7,9,11,13H,8,10,12H2,(H,27,31)(H,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28774
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES Cc1ccccc1-c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1
Show InChI InChI=1S/C27H22Cl2N2O5/c1-16-5-2-3-8-20(16)26-24(25(31-36-26)18-7-4-6-17(13-18)14-23(32)33)27(34)30-11-12-35-22-10-9-19(28)15-21(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28775
PNG
(2-{3-[5-(2-chlorophenyl)-4-{[2-(2,4-dichlorophenox...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1Cl
Show InChI InChI=1S/C26H19Cl3N2O5/c27-17-8-9-21(20(29)14-17)35-11-10-30-26(34)23-24(16-5-3-4-15(12-16)13-22(32)33)31-36-25(23)18-6-1-2-7-19(18)28/h1-9,12,14H,10-11,13H2,(H,30,34)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28764
PNG
(2-[3-chloro-4-(4-{[2-(2,4-dichlorophenoxy)ethyl]ca...)
Show SMILES OC(=O)Cc1ccc(-c2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C26H19Cl3N2O5/c27-17-7-9-21(20(29)14-17)35-11-10-30-26(34)23-24(31-36-25(23)16-4-2-1-3-5-16)18-8-6-15(12-19(18)28)13-22(32)33/h1-9,12,14H,10-11,13H2,(H,30,34)(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28765
PNG
(2-{3-chloro-4-[(4-{[2-(2,4-dichlorophenoxy)ethyl]c...)
Show SMILES OC(=O)Cc1ccc(OCc2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C27H21Cl3N2O6/c28-18-7-9-22(20(30)14-18)36-11-10-31-27(35)25-21(32-38-26(25)17-4-2-1-3-5-17)15-37-23-8-6-16(12-19(23)29)13-24(33)34/h1-9,12,14H,10-11,13,15H2,(H,31,35)(H,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28766
PNG
(2-[4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1ccc(cc1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-10-11-21(20(28)15-19)34-13-12-29-26(33)23-24(17-8-6-16(7-9-17)14-22(31)32)30-35-25(23)18-4-2-1-3-5-18/h1-11,15H,12-14H2,(H,29,33)(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28767
PNG
(4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-5-p...)
Show SMILES OC(=O)c1ccc(cc1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C25H18Cl2N2O5/c26-18-10-11-20(19(27)14-18)33-13-12-28-24(30)21-22(15-6-8-17(9-7-15)25(31)32)29-34-23(21)16-4-2-1-3-5-16/h1-11,14H,12-13H2,(H,28,30)(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28768
PNG
(2-[4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES Cc1cc(ccc1OCC(O)=O)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O6/c1-16-13-18(7-9-21(16)36-15-23(32)33)25-24(26(37-31-25)17-5-3-2-4-6-17)27(34)30-11-12-35-22-10-8-19(28)14-20(22)29/h2-10,13-14H,11-12,15H2,1H3,(H,30,34)(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28769
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-9-10-21(20(28)15-19)34-12-11-29-26(33)23-24(18-8-4-5-16(13-18)14-22(31)32)30-35-25(23)17-6-2-1-3-7-17/h1-10,13,15H,11-12,14H2,(H,29,33)(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28770
PNG
(3-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)CCc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O5/c28-20-10-11-22(21(29)16-20)35-14-13-30-27(34)24-25(31-36-26(24)18-6-2-1-3-7-18)19-8-4-5-17(15-19)9-12-23(32)33/h1-8,10-11,15-16H,9,12-14H2,(H,30,34)(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28771
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES COc1ccc(CC(O)=O)cc1-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1
Show InChI InChI=1S/C27H22Cl2N2O6/c1-35-21-9-7-16(14-23(32)33)13-19(21)25-24(26(37-31-25)17-5-3-2-4-6-17)27(34)30-11-12-36-22-10-8-18(28)15-20(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28772
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES CC(C)c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1
Show InChI InChI=1S/C23H22Cl2N2O5/c1-13(2)22-20(21(27-32-22)15-5-3-4-14(10-15)11-19(28)29)23(30)26-8-9-31-18-7-6-16(24)12-17(18)25/h3-7,10,12-13H,8-9,11H2,1-2H3,(H,26,30)(H,28,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28773
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(-c2ccco2)c1C(=O)NCCOc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H18Cl2N2O6/c25-16-6-7-18(17(26)13-16)33-10-8-27-24(31)21-22(28-34-23(21)19-5-2-9-32-19)15-4-1-3-14(11-15)12-20(29)30/h1-7,9,11,13H,8,10,12H2,(H,27,31)(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28774
PNG
(2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...)
Show SMILES Cc1ccccc1-c1onc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1cccc(CC(O)=O)c1
Show InChI InChI=1S/C27H22Cl2N2O5/c1-16-5-2-3-8-20(16)26-24(25(31-36-26)18-7-4-6-17(13-18)14-23(32)33)27(34)30-11-12-35-22-10-9-19(28)15-21(22)29/h2-10,13,15H,11-12,14H2,1H3,(H,30,34)(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28775
PNG
(2-{3-[5-(2-chlorophenyl)-4-{[2-(2,4-dichlorophenox...)
Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1Cl
Show InChI InChI=1S/C26H19Cl3N2O5/c27-17-8-9-21(20(29)14-17)35-11-10-30-26(34)23-24(16-5-3-4-15(12-16)13-22(32)33)31-36-25(23)18-6-1-2-7-19(18)28/h1-9,12,14H,10-11,13H2,(H,30,34)(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



GNF



Assay Description
EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...


Bioorg Med Chem Lett 16: 5488-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.052
BindingDB Entry DOI: 10.7270/Q23X84Z3
More data for this
Ligand-Target Pair
Beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50002595
PNG
(SOLABEGRON | Solabegron)
Show SMILES O[C@@H](CNCCNc1cccc(c1)-c1cccc(c1)C(O)=O)c1cccc(Cl)c1
Show InChI InChI=1S/C23H23ClN2O3/c24-20-8-2-6-18(13-20)22(27)15-25-10-11-26-21-9-3-5-17(14-21)16-4-1-7-19(12-16)23(28)29/h1-9,12-14,22,25-27H,10-11,15H2,(H,28,29)/t22-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP production


J Med Chem 49: 2758-71 (2006)

Checked by Author
Article DOI: 10.1021/jm0509445
BindingDB Entry DOI: 10.7270/Q2KD20D5
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50002596
PNG
(CHEMBL424866)
Show SMILES O[C@@H](CNCCNc1cccc(c1)-c1cccc(n1)C(O)=O)c1cccc(Cl)c1
Show InChI InChI=1S/C22H22ClN3O3/c23-17-6-1-5-16(12-17)21(27)14-24-10-11-25-18-7-2-4-15(13-18)19-8-3-9-20(26-19)22(28)29/h1-9,12-13,21,24-25,27H,10-11,14H2,(H,28,29)/t21-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Activity at human beta-2 adrenergic receptor expressed in CHO cells by stimulation of cAMP production


J Med Chem 49: 2758-71 (2006)

Checked by Author
Article DOI: 10.1021/jm0509445
BindingDB Entry DOI: 10.7270/Q2KD20D5
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50002597
PNG
(CHEMBL377028)
Show SMILES C[C@H](CNc1cccc(c1)-c1ccccc1C(O)=O)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C24H25ClN2O3/c1-16(26-15-23(28)18-7-4-8-19(25)12-18)14-27-20-9-5-6-17(13-20)21-10-2-3-11-22(21)24(29)30/h2-13,16,23,26-28H,14-15H2,1H3,(H,29,30)/t16-,23+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 631n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP production


J Med Chem 49: 2758-71 (2006)

Checked by Author
Article DOI: 10.1021/jm0509445
BindingDB Entry DOI: 10.7270/Q2KD20D5
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50422411
PNG
(CHEMBL154419)
Show SMILES C[C@H](CNc1ccc(CC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C19H23ClN2O3/c1-13(21-12-18(23)15-3-2-4-16(20)10-15)11-22-17-7-5-14(6-8-17)9-19(24)25/h2-8,10,13,18,21-23H,9,11-12H2,1H3,(H,24,25)/t13-,18+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 79n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP production


J Med Chem 49: 2758-71 (2006)

Checked by Author
Article DOI: 10.1021/jm0509445
BindingDB Entry DOI: 10.7270/Q2KD20D5
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50002595
PNG
(SOLABEGRON | Solabegron)
Show SMILES O[C@@H](CNCCNc1cccc(c1)-c1cccc(c1)C(O)=O)c1cccc(Cl)c1
Show InChI InChI=1S/C23H23ClN2O3/c24-20-8-2-6-18(13-20)22(27)15-25-10-11-26-21-9-3-5-17(14-21)16-4-1-7-19(12-16)23(28)29/h1-9,12-14,22,25-27H,10-11,15H2,(H,28,29)/t22-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.98E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Activity at human beta-1 adrenergic receptor expressed in CHO cells by stimulation of cAMP production


J Med Chem 49: 2758-71 (2006)

Checked by Author
Article DOI: 10.1021/jm0509445
BindingDB Entry DOI: 10.7270/Q2KD20D5
More data for this
Ligand-Target Pair
Beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50002598
PNG
(CHEMBL152535)
Show SMILES C[C@H](Cc1ccc(OCC([O-])=O)cc1)NC[C@H](O)c1cccc(Cl)c1
Show InChI InChI=1S/C19H22ClNO4.Na/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24;/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24);/q;+1/p-1/t13-,18+;/m1./s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 25n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Activity at human beta-3 adrenergic receptor expressed in CHO cells by stimulation of cAMP production


J Med Chem 49: 2758-71 (2006)

Checked by Author
Article DOI: 10.1021/jm0509445
BindingDB Entry DOI: 10.7270/Q2KD20D5
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 720 total )  |  Next  |  Last  >>
Jump to: