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Compile Data Set for Download or QSAR

Found 54 hits with Last Name = 'deiana' and Initial = 'v'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Homo sapiens (Human))
BDBM50143320
PNG
((+)-epibatidine | (-)-1-epidatidine | (1S,2S,4R)-2...)
Show SMILES Clc1ccc(cn1)[C@@H]1C[C@H]2CC[C@@H]1N2 |THB:4:7:13:11.10|
Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m1/s1
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0.0450n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Binding affinity to alpha4beta2 nAChR (unknown origin)


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152111
PNG
(CHEMBL3781178)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2Cc3cc(ccc3-c12)C1CC1 |TLB:21:16:23:19.20.22,21:20:23:17.16.15,THB:19:18:15:21.20.22,19:20:17.18.23:15|
Show InChI InChI=1S/C30H29Cl2N3O/c31-22-4-6-26(25(32)12-22)35-28-23-5-3-20(19-1-2-19)10-21(23)11-24(28)27(34-35)29(36)33-30-13-16-7-17(14-30)9-18(8-16)15-30/h3-6,10,12,16-19H,1-2,7-9,11,13-15H2,(H,33,36)
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4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152116
PNG
(CHEMBL3781131)
Show SMILES C[C@]12CCC(C1)C(C)(C)C2NC(=O)c1nn(c-2c1Cc1cc(ccc-21)C1CC1)-c1ccc(Cl)cc1Cl |r|
Show InChI InChI=1/C30H31Cl2N3O/c1-29(2)19-10-11-30(3,15-19)28(29)33-27(36)25-22-13-18-12-17(16-4-5-16)6-8-21(18)26(22)35(34-25)24-9-7-20(31)14-23(24)32/h6-9,12,14,16,19,28H,4-5,10-11,13,15H2,1-3H3,(H,33,36)/t19?,28?,30-/s2
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6n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM60994
PNG
((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Show SMILES CCCCCc1cc(O)c2[C@@H]3C=C(C)CC[C@H]3C(C)(C)Oc2c1 |r,t:11|
Show InChI InChI=1/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h11-13,16-17,22H,5-10H2,1-4H3/t16-,17-/s2
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36n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]HU-243 from CB1 receptor in Sprague-Dawley rat brain incubated for 90 mins


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152112
PNG
(CHEMBL3780792)
Show SMILES [H][C@@]12CC[C@](C)([C@@H](C1)NC(=O)c1nn(c-3c1Cc1cc(ccc-31)C1CC1)-c1ccc(Cl)cc1Cl)C2(C)C |r,TLB:8:6:34:2.3|
Show InChI InChI=1/C30H31Cl2N3O/c1-29(2)19-10-11-30(29,3)25(14-19)33-28(36)26-22-13-18-12-17(16-4-5-16)6-8-21(18)27(22)35(34-26)24-9-7-20(31)15-23(24)32/h6-9,12,15-16,19,25H,4-5,10-11,13-14H2,1-3H3,(H,33,36)/t19-,25-,30-/s2
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38n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152102
PNG
(CHEMBL3781781)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2Cc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C25H24Cl2N4O/c26-18-7-9-22(21(27)14-18)31-24-19-8-6-16(15-4-5-15)12-17(19)13-20(24)23(28-31)25(32)29-30-10-2-1-3-11-30/h6-9,12,14-15H,1-5,10-11,13H2,(H,29,32)
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69n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127648
PNG
(CHEMBL3628495)
Show SMILES Clc1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C10H12ClN3/c11-7-1-10(4-12-3-7)14-5-8-2-9(6-14)13-8/h1,3-4,8-9,13H,2,5-6H2
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73n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM22988
PNG
((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
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89n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from CB1 receptor in Wistar rat brain incubated for 60 mins by radioactive filter binding assay


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152121
PNG
(CHEMBL3781726)
Show SMILES Cl.Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2CCc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C26H26Cl2N4O.ClH/c27-19-8-11-23(22(28)15-19)32-25-20-9-6-17(16-4-5-16)14-18(20)7-10-21(25)24(29-32)26(33)30-31-12-2-1-3-13-31;/h6,8-9,11,14-16H,1-5,7,10,12-13H2,(H,30,33);1H
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143n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152110
PNG
(CHEMBL3780457)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCC2)c2Cc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C24H22Cl2N4O/c25-17-6-8-21(20(26)13-17)30-23-18-7-5-15(14-3-4-14)11-16(18)12-19(23)22(27-30)24(31)28-29-9-1-2-10-29/h5-8,11,13-14H,1-4,9-10,12H2,(H,28,31)
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152n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127655
PNG
(CHEMBL3628496)
Show SMILES Brc1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C10H12BrN3/c11-7-1-10(4-12-3-7)14-5-8-2-9(6-14)13-8/h1,3-4,8-9,13H,2,5-6H2
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176n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152109
PNG
(CHEMBL3781707)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCOCC2)c2Cc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C24H22Cl2N4O2/c25-17-4-6-21(20(26)13-17)30-23-18-5-3-15(14-1-2-14)11-16(18)12-19(23)22(27-30)24(31)28-29-7-9-32-10-8-29/h3-6,11,13-14H,1-2,7-10,12H2,(H,28,31)
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198n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152108
PNG
(CHEMBL3780282)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)N2CCCCC2)c2Cc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C25H23Cl2N3O/c26-18-7-9-22(21(27)14-18)30-24-19-8-6-16(15-4-5-15)12-17(19)13-20(24)23(28-30)25(31)29-10-2-1-3-11-29/h6-9,12,14-15H,1-5,10-11,13H2
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414n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM26144
PNG
(1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC(CO)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
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472n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from CB1 receptor in Wistar rat brain incubated for 60 mins by radioactive filter binding assay


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152117
PNG
(CHEMBL3781351)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2Cc3cc(ccc3-c12)C1CCCCC1
Show InChI InChI=1S/C28H30Cl2N4O/c29-21-10-12-25(24(30)17-21)34-27-22-11-9-19(18-7-3-1-4-8-18)15-20(22)16-23(27)26(31-34)28(35)32-33-13-5-2-6-14-33/h9-12,15,17-18H,1-8,13-14,16H2,(H,32,35)
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509n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152103
PNG
(CHEMBL3780680)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCC2)c2Cc3cc(ccc3-c12)C1CCCCC1
Show InChI InChI=1S/C27H28Cl2N4O/c28-20-9-11-24(23(29)16-20)33-26-21-10-8-18(17-6-2-1-3-7-17)14-19(21)15-22(26)25(30-33)27(34)31-32-12-4-5-13-32/h8-11,14,16-17H,1-7,12-13,15H2,(H,31,34)
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515n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152120
PNG
(CHEMBL3780775)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2ccc3cc(ccc3c12)C1CC1
Show InChI InChI=1S/C26H24Cl2N4O/c27-19-8-11-23(22(28)15-19)32-25-20-9-6-17(16-4-5-16)14-18(20)7-10-21(25)24(29-32)26(33)30-31-12-2-1-3-13-31/h6-11,14-16H,1-5,12-13H2,(H,30,33)
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825n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152102
PNG
(CHEMBL3781781)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2Cc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C25H24Cl2N4O/c26-18-7-9-22(21(27)14-18)31-24-19-8-6-16(15-4-5-15)12-17(19)13-20(24)23(28-31)25(32)29-30-10-2-1-3-11-30/h6-9,12,14-15H,1-5,10-11,13H2,(H,29,32)
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1.85E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152109
PNG
(CHEMBL3781707)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCOCC2)c2Cc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C24H22Cl2N4O2/c25-17-4-6-21(20(26)13-17)30-23-18-5-3-15(14-1-2-14)11-16(18)12-19(23)22(27-30)24(31)28-29-7-9-32-10-8-29/h3-6,11,13-14H,1-2,7-10,12H2,(H,28,31)
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4.03E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152110
PNG
(CHEMBL3780457)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCC2)c2Cc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C24H22Cl2N4O/c25-17-6-8-21(20(26)13-17)30-23-18-7-5-15(14-3-4-14)11-16(18)12-19(23)22(27-30)24(31)28-29-9-1-2-10-29/h5-8,11,13-14H,1-4,9-10,12H2,(H,28,31)
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4.21E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127663
PNG
(CHEMBL3628504)
Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C16H16N4O2/c21-20(22)15-3-1-11(2-4-15)12-5-16(8-17-7-12)19-9-13-6-14(10-19)18-13/h1-5,7-8,13-14,18H,6,9-10H2
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5.00E+3n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152115
PNG
(CHEMBL3781252)
Show SMILES C[C@]12CCC(C1)C(C)(C)C2NC(=O)c1nn(c-2c1CCc1cc(ccc-21)C1CC1)-c1ccc(Cl)cc1Cl |r|
Show InChI InChI=1/C31H33Cl2N3O/c1-30(2)20-12-13-31(3,16-20)29(30)34-28(37)26-23-10-7-19-14-18(17-4-5-17)6-9-22(19)27(23)36(35-26)25-11-8-21(32)15-24(25)33/h6,8-9,11,14-15,17,20,29H,4-5,7,10,12-13,16H2,1-3H3,(H,34,37)/t20?,29?,31-/s2
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5.52E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127662
PNG
(CHEMBL3628503)
Show SMILES Clc1ccc(Cl)c(c1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C16H15Cl2N3/c17-11-1-2-16(18)15(4-11)10-3-14(7-19-6-10)21-8-12-5-13(9-21)20-12/h1-4,6-7,12-13,20H,5,8-9H2
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6.00E+3n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127665
PNG
(CHEMBL3628506)
Show SMILES COc1ccc(cc1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C17H19N3O/c1-21-17-4-2-12(3-5-17)13-6-16(9-18-8-13)20-10-14-7-15(11-20)19-14/h2-6,8-9,14-15,19H,7,10-11H2,1H3
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6.50E+3n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152107
PNG
(CHEMBL3780368)
Show SMILES CC1(C)C2CC1C(CNC(=O)c1nn(c-3c1CCc1cc(ccc-31)C1CC1)-c1ccc(Cl)cc1Cl)CC2 |THB:7:6:1:4|
Show InChI InChI=1/C31H33Cl2N3O/c1-31(2)21-8-5-20(25(31)14-21)16-34-30(37)28-24-11-7-19-13-18(17-3-4-17)6-10-23(19)29(24)36(35-28)27-12-9-22(32)15-26(27)33/h6,9-10,12-13,15,17,20-21,25H,3-5,7-8,11,14,16H2,1-2H3,(H,34,37)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152117
PNG
(CHEMBL3781351)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2Cc3cc(ccc3-c12)C1CCCCC1
Show InChI InChI=1S/C28H30Cl2N4O/c29-21-10-12-25(24(30)17-21)34-27-22-11-9-19(18-7-3-1-4-8-18)15-20(22)16-23(27)26(31-34)28(35)32-33-13-5-2-6-14-33/h9-12,15,17-18H,1-8,13-14,16H2,(H,32,35)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152113
PNG
(CHEMBL3781542)
Show SMILES C[C@]12CCC(C1)C(C)(C)C2NC(=O)c1nn(c-2c1Cc1cc(ccc-21)C1CCCCC1)-c1ccc(Cl)cc1Cl |r|
Show InChI InChI=1/C33H37Cl2N3O/c1-32(2)22-13-14-33(3,18-22)31(32)36-30(39)28-25-16-21-15-20(19-7-5-4-6-8-19)9-11-24(21)29(25)38(37-28)27-12-10-23(34)17-26(27)35/h9-12,15,17,19,22,31H,4-8,13-14,16,18H2,1-3H3,(H,36,39)/t22?,31?,33-/s2
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152113
PNG
(CHEMBL3781542)
Show SMILES C[C@]12CCC(C1)C(C)(C)C2NC(=O)c1nn(c-2c1Cc1cc(ccc-21)C1CCCCC1)-c1ccc(Cl)cc1Cl |r|
Show InChI InChI=1/C33H37Cl2N3O/c1-32(2)22-13-14-33(3,18-22)31(32)36-30(39)28-25-16-21-15-20(19-7-5-4-6-8-19)9-11-24(21)29(25)38(37-28)27-12-10-23(34)17-26(27)35/h9-12,15,17,19,22,31H,4-8,13-14,16,18H2,1-3H3,(H,36,39)/t22?,31?,33-/s2
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Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152111
PNG
(CHEMBL3781178)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2Cc3cc(ccc3-c12)C1CC1 |TLB:21:16:23:19.20.22,21:20:23:17.16.15,THB:19:18:15:21.20.22,19:20:17.18.23:15|
Show InChI InChI=1S/C30H29Cl2N3O/c31-22-4-6-26(25(32)12-22)35-28-23-5-3-20(19-1-2-19)10-21(23)11-24(28)27(34-35)29(36)33-30-13-16-7-17(14-30)9-18(8-16)15-30/h3-6,10,12,16-19H,1-2,7-9,11,13-15H2,(H,33,36)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152103
PNG
(CHEMBL3780680)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCC2)c2Cc3cc(ccc3-c12)C1CCCCC1
Show InChI InChI=1S/C27H28Cl2N4O/c28-20-9-11-24(23(29)16-20)33-26-21-10-8-18(17-6-2-1-3-7-17)14-19(21)15-22(26)25(30-33)27(34)31-32-12-4-5-13-32/h8-11,14,16-17H,1-7,12-13,15H2,(H,31,34)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152107
PNG
(CHEMBL3780368)
Show SMILES CC1(C)C2CC1C(CNC(=O)c1nn(c-3c1CCc1cc(ccc-31)C1CC1)-c1ccc(Cl)cc1Cl)CC2 |THB:7:6:1:4|
Show InChI InChI=1/C31H33Cl2N3O/c1-31(2)21-8-5-20(25(31)14-21)16-34-30(37)28-24-11-7-19-13-18(17-3-4-17)6-10-23(19)29(24)36(35-28)27-12-9-22(32)15-26(27)33/h6,9-10,12-13,15,17,20-21,25H,3-5,7-8,11,14,16H2,1-2H3,(H,34,37)
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Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152108
PNG
(CHEMBL3780282)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)N2CCCCC2)c2Cc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C25H23Cl2N3O/c26-18-7-9-22(21(27)14-18)30-24-19-8-6-16(15-4-5-15)12-17(19)13-20(24)23(28-30)25(31)29-10-2-1-3-11-29/h6-9,12,14-15H,1-5,10-11,13H2
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Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127660
PNG
(CHEMBL3628501)
Show SMILES Clc1ccc(c(Cl)c1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C16H15Cl2N3/c17-11-1-2-15(16(18)4-11)10-3-14(7-19-6-10)21-8-12-5-13(9-21)20-12/h1-4,6-7,12-13,20H,5,8-9H2
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1.30E+4n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127656
PNG
(CHEMBL3628497)
Show SMILES C1C2CN(CC1N2)c1cncc(c1)-c1ccccc1
Show InChI InChI=1/C16H17N3/c1-2-4-12(5-3-1)13-6-16(9-17-8-13)19-10-14-7-15(11-19)18-14/h1-6,8-9,14-15,18H,7,10-11H2
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1.70E+4n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127659
PNG
(CHEMBL3628500)
Show SMILES Brc1ccc(cc1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C16H16BrN3/c17-13-3-1-11(2-4-13)12-5-16(8-18-7-12)20-9-14-6-15(10-20)19-14/h1-5,7-8,14-15,19H,6,9-10H2
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3.40E+4n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127661
PNG
(CHEMBL3628502)
Show SMILES Clc1ccc(cc1Cl)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C16H15Cl2N3/c17-15-2-1-10(4-16(15)18)11-3-14(7-19-6-11)21-8-12-5-13(9-21)20-12/h1-4,6-7,12-13,20H,5,8-9H2
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3.60E+4n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152104
PNG
(CHEMBL3780960)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)N2CCCCC2)c2ccc3cc(ccc3c12)C1CC1
Show InChI InChI=1S/C26H23Cl2N3O/c27-19-8-11-23(22(28)15-19)31-25-20-9-6-17(16-4-5-16)14-18(20)7-10-21(25)24(29-31)26(32)30-12-2-1-3-13-30/h6-11,14-16H,1-5,12-13H2
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152106
PNG
(CHEMBL3780124)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCC2)c2ccc3cc(ccc3c12)C1CC1
Show InChI InChI=1S/C25H22Cl2N4O/c26-18-7-10-22(21(27)14-18)31-24-19-8-5-16(15-3-4-15)13-17(19)6-9-20(24)23(28-31)25(32)29-30-11-1-2-12-30/h5-10,13-15H,1-4,11-12H2,(H,29,32)
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152112
PNG
(CHEMBL3780792)
Show SMILES [H][C@@]12CC[C@](C)([C@@H](C1)NC(=O)c1nn(c-3c1Cc1cc(ccc-31)C1CC1)-c1ccc(Cl)cc1Cl)C2(C)C |r,TLB:8:6:34:2.3|
Show InChI InChI=1/C30H31Cl2N3O/c1-29(2)19-10-11-30(29,3)25(14-19)33-28(36)26-22-13-18-12-17(16-4-5-16)6-8-21(18)27(22)35(34-26)24-9-7-20(31)15-23(24)32/h6-9,12,15-16,19,25H,4-5,10-11,13-14H2,1-3H3,(H,33,36)/t19-,25-,30-/s2
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152114
PNG
(CHEMBL3780608)
Show SMILES Cl.C[C@]12CCC(C1)C(C)(C)C2NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1ccc1cc(ccc21)C1CC1 |r|
Show InChI InChI=1/C31H31Cl2N3O.ClH/c1-30(2)20-12-13-31(3,16-20)29(30)34-28(37)26-23-10-7-19-14-18(17-4-5-17)6-9-22(19)27(23)36(35-26)25-11-8-21(32)15-24(25)33;/h6-11,14-15,17,20,29H,4-5,12-13,16H2,1-3H3,(H,34,37);1H/t20?,29?,31-;/s2
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152114
PNG
(CHEMBL3780608)
Show SMILES Cl.C[C@]12CCC(C1)C(C)(C)C2NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1ccc1cc(ccc21)C1CC1 |r|
Show InChI InChI=1/C31H31Cl2N3O.ClH/c1-30(2)20-12-13-31(3,16-20)29(30)34-28(37)26-23-10-7-19-14-18(17-4-5-17)6-9-22(19)27(23)36(35-26)25-11-8-21(32)15-24(25)33;/h6-11,14-15,17,20,29H,4-5,12-13,16H2,1-3H3,(H,34,37);1H/t20?,29?,31-;/s2
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152115
PNG
(CHEMBL3781252)
Show SMILES C[C@]12CCC(C1)C(C)(C)C2NC(=O)c1nn(c-2c1CCc1cc(ccc-21)C1CC1)-c1ccc(Cl)cc1Cl |r|
Show InChI InChI=1/C31H33Cl2N3O/c1-30(2)20-12-13-31(3,16-20)29(30)34-28(37)26-23-10-7-19-14-18(17-4-5-17)6-9-22(19)27(23)36(35-26)25-11-8-21(32)15-24(25)33/h6,8-9,11,14-15,17,20,29H,4-5,7,10,12-13,16H2,1-3H3,(H,34,37)/t20?,29?,31-/s2
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152116
PNG
(CHEMBL3781131)
Show SMILES C[C@]12CCC(C1)C(C)(C)C2NC(=O)c1nn(c-2c1Cc1cc(ccc-21)C1CC1)-c1ccc(Cl)cc1Cl |r|
Show InChI InChI=1/C30H31Cl2N3O/c1-29(2)19-10-11-30(3,15-19)28(29)33-27(36)25-22-13-18-12-17(16-4-5-16)6-8-21(18)26(22)35(34-25)24-9-7-20(31)14-23(24)32/h6-9,12,14,16,19,28H,4-5,10-11,13,15H2,1-3H3,(H,33,36)/t19?,28?,30-/s2
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152104
PNG
(CHEMBL3780960)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)N2CCCCC2)c2ccc3cc(ccc3c12)C1CC1
Show InChI InChI=1S/C26H23Cl2N3O/c27-19-8-11-23(22(28)15-19)31-25-20-9-6-17(16-4-5-16)14-18(20)7-10-21(25)24(29-31)26(32)30-12-2-1-3-13-30/h6-11,14-16H,1-5,12-13H2
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50152106
PNG
(CHEMBL3780124)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCC2)c2ccc3cc(ccc3c12)C1CC1
Show InChI InChI=1S/C25H22Cl2N4O/c26-18-7-10-22(21(27)14-18)31-24-19-8-5-16(15-3-4-15)13-17(19)6-9-20(24)23(28-31)25(32)29-30-11-1-2-12-30/h5-10,13-15H,1-4,11-12H2,(H,29,32)
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152121
PNG
(CHEMBL3781726)
Show SMILES Cl.Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2CCc3cc(ccc3-c12)C1CC1
Show InChI InChI=1S/C26H26Cl2N4O.ClH/c27-19-8-11-23(22(28)15-19)32-25-20-9-6-17(16-4-5-16)14-18(20)7-10-21(25)24(29-32)26(33)30-31-12-2-1-3-13-31;/h6,8-9,11,14-16H,1-5,7,10,12-13H2,(H,30,33);1H
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50152120
PNG
(CHEMBL3780775)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NN2CCCCC2)c2ccc3cc(ccc3c12)C1CC1
Show InChI InChI=1S/C26H24Cl2N4O/c27-19-8-11-23(22(28)15-19)32-25-20-9-6-17(16-4-5-16)14-18(20)7-10-21(25)24(29-32)26(33)30-31-12-2-1-3-13-31/h6-11,14-16H,1-5,12-13H2,(H,30,33)
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>4.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293-EBNA cell membrane incubated for 90 mins by liquid scintillation counting met...


Eur J Med Chem 112: 66-80 (2016)


BindingDB Entry DOI: 10.7270/Q24B336C
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127657
PNG
(CHEMBL3628498)
Show SMILES Clc1ccc(cc1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C16H16ClN3/c17-13-3-1-11(2-4-13)12-5-16(8-18-7-12)20-9-14-6-15(10-20)19-14/h1-5,7-8,14-15,19H,6,9-10H2
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4.80E+4n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127664
PNG
(CHEMBL3628505)
Show SMILES Cc1ccc(cc1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C17H19N3/c1-12-2-4-13(5-3-12)14-6-17(9-18-8-14)20-10-15-7-16(11-20)19-15/h2-6,8-9,15-16,19H,7,10-11H2,1H3
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9.60E+4n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50127658
PNG
(CHEMBL3628499)
Show SMILES Fc1ccc(cc1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1/C16H16FN3/c17-13-3-1-11(2-4-13)12-5-16(8-18-7-12)20-9-14-6-15(10-20)19-14/h1-5,7-8,14-15,19H,6,9-10H2
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1.10E+5n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...


Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair
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